E
Edward D. Huey
Researcher at Columbia University
Publications - 137
Citations - 4188
Edward D. Huey is an academic researcher from Columbia University. The author has contributed to research in topics: Frontotemporal dementia & Dementia. The author has an hindex of 27, co-authored 113 publications receiving 2930 citations. Previous affiliations of Edward D. Huey include Columbia University Medical Center & National Institutes of Health.
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Journal ArticleDOI
Frontotemporal dementia and its subtypes: a genome-wide association study
Raffaele Ferrari,Raffaele Ferrari,Dena G. Hernandez,Dena G. Hernandez,Mike A. Nalls,Jonathan D. Rohrer,Adaikalavan Ramasamy,Adaikalavan Ramasamy,John B.J. Kwok,John B.J. Kwok,Carol Dobson-Stone,Carol Dobson-Stone,William S. Brooks,William S. Brooks,Peter R. Schofield,Peter R. Schofield,Glenda M. Halliday,Glenda M. Halliday,John R. Hodges,John R. Hodges,Olivier Piguet,Olivier Piguet,Lauren Bartley,Elizabeth Thompson,Elizabeth Thompson,Eric Haan,Eric Haan,Isabel Hernández,Agustín Ruiz,Mercè Boada,Barbara Borroni,Alessandro Padovani,Carlos Cruchaga,Nigel J. Cairns,Luisa Benussi,Giuliano Binetti,Roberta Ghidoni,Gianluigi Forloni,Daniela Galimberti,Chiara Fenoglio,Maria Serpente,Elio Scarpini,Jordi Clarimón,Alberto Lleó,Rafael Blesa,Maria Landqvist Waldö,Karin Nilsson,Christer Nilsson,Ian R. A. Mackenzie,Ging-Yuek Robin Hsiung,David M. A. Mann,Jordan Grafman,Jordan Grafman,Jordan Grafman,Christopher Morris,Johannes Attems,Timothy D. Griffiths,Ian G. McKeith,Alan J. Thomas,Pietro Pietrini,Edward D. Huey,Eric M. Wassermann,Atik Baborie,Evelyn Jaros,Evelyn Jaros,Michael Tierney,Pau Pastor,Cristina Razquin,Sara Ortega-Cubero,Elena Alonso,Robert Perneczky,Robert Perneczky,Janine Diehl-Schmid,Panagiotis Alexopoulos,Alexander Kurz,Innocenzo Rainero,Elisa Rubino,Lorenzo Pinessi,Ekaterina Rogaeva,Peter St George-Hyslop,Peter St George-Hyslop,Giacomina Rossi,Fabrizio Tagliavini,Giorgio Giaccone,James B. Rowe,James B. Rowe,Johannes C. M. Schlachetzki,Johannes C. M. Schlachetzki,James Uphill,John Collinge,Simon Mead,Adrian Danek,Adrian Danek,Vivianna M. Van Deerlin,Murray Grossman,John Q. Trojanowski,Julie van der Zee,William Deschamps,Tim Van Langenhove,Marc Cruts,Christine Van Broeckhoven,Stefano F. Cappa,Isabelle Le Ber,Didier Hannequin,Véronique Golfier,Martine Vercelletto,Alexis Brice,Benedetta Nacmias,Sandro Sorbi,Silvia Bagnoli,Irene Piaceri,Jørgen E. Nielsen,Jørgen E. Nielsen,Lena E. Hjermind,Lena E. Hjermind,Matthias Riemenschneider,Manuel Mayhaus,Bernd Ibach,Gilles Gasparoni,Sabrina Pichler,Wei Gu,Wei Gu,Martin N. Rossor,Nick C. Fox,Jason D. Warren,Maria Grazia Spillantini,Huw R. Morris,Patrizia Rizzu,Peter Heutink,Julie S. Snowden,Sara Rollinson,Anna Richardson,Alexander Gerhard,Amalia C. Bruni,Raffaele Maletta,Francesca Frangipane,Chiara Cupidi,Livia Bernardi,Maria Anfossi,Maura Gallo,Maria Elena Conidi,Nicoletta Smirne,Rosa Rademakers,Matthew C. Baker,Dennis W. Dickson,Neill R. Graff-Radford,Ronald C. Petersen,David S. Knopman,Keith A. Josephs,Bradley F. Boeve,Joseph E. Parisi,William W. Seeley,Bruce L. Miller,Anna Karydas,Howard J. Rosen,John C. van Swieten,John C. van Swieten,Elise G.P. Dopper,Harro Seelaar,Yolande A.L. Pijnenburg,Philip Scheltens,Giancarlo Logroscino,Rosa Capozzo,Valeria Novelli,Annibale Alessandro Puca,Massimo Franceschi,Alfredo Postiglione,Graziella Milan,Paolo Sorrentino,Mark Kristiansen,Huei-Hsin Chiang,Caroline Graff,Florence Pasquier,Adeline Rollin,Vincent Deramecourt,Florence Lebert,Dimitrios Kapogiannis,Luigi Ferrucci,Stuart Pickering-Brown,Andrew B. Singleton,John Hardy,Parastoo Momeni +181 more
TL;DR: The findings suggest that immune system processes (link to 6p21.3) and possibly lysosomal and autophagy pathways ( link to 11q14) are potentially involved in FTD.
Journal ArticleDOI
A systematic review of neurotransmitter deficits and treatments in frontotemporal dementia.
TL;DR: Studies of neurotransmitter deficiencies in frontotemporal dementia (FTD) can be helpful in developing treatments, and larger, well-controlled treatment studies are required to reach more definitive conclusions about treatment efficacy.
Journal ArticleDOI
FTD and ALS: a tale of two diseases.
TL;DR: A better understanding of the clinical, pathological and genetic features characterizing FTD and ALS will shed light into overlaps among these two disorders and the underpinning mechanisms that contribute to the onset and development.
Journal ArticleDOI
Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study.
Katrina M. Moore,Jennifer M. Nicholas,Murray Grossman,Corey T. McMillan,David J. Irwin,Lauren Massimo,Vivianna M. Van Deerlin,Jason D. Warren,Nick C. Fox,Martin N. Rossor,Simon Mead,Martina Bocchetta,Bradley F. Boeve,David S. Knopman,Neill Graff-Radford,Leah K. Forsberg,Rosa Rademakers,Zbigniew K. Wszolek,John C. van Swieten,Lize C. Jiskoot,Lieke H.H. Meeter,Elise G.P. Dopper,Janne M. Papma,Julie S. Snowden,Jennifer A. Saxon,Matthew Jones,Stuart Pickering-Brown,Isabelle Le Ber,Agnès Camuzat,Alexis Brice,Paola Caroppo,Roberta Ghidoni,Michela Pievani,Luisa Benussi,Giuliano Binetti,Bradford C. Dickerson,Diane Lucente,Samantha Krivensky,Caroline Graff,Linn Öijerstedt,Marie Fallström,Håkan Thonberg,Nupur Ghoshal,John C. Morris,Barbara Borroni,Alberto Benussi,Alessandro Padovani,Daniela Galimberti,Elio Scarpini,Giorgio G. Fumagalli,Giorgio G. Fumagalli,Ian R. Mackenzie,Ging-Yuek Robin Hsiung,Pheth Sengdy,Adam L. Boxer,Howie Rosen,Joanne Taylor,Matthis Synofzik,Matthis Synofzik,Carlo Wilke,Carlo Wilke,Patricia Sulzer,Patricia Sulzer,John R. Hodges,Glenda M. Halliday,John B.J. Kwok,Raquel Sánchez-Valle,Albert Lladó,Sergi Borrego-Écija,Isabel Santana,Maria Rosário Almeida,Miguel Tábuas-Pereira,Fermin Moreno,Myriam Barandiaran,Begoña Indakoetxea,Johannes Levin,Johannes Levin,Adrian Danek,James B. Rowe,Thomas E. Cope,Markus Otto,Sarah Anderl-Straub,Alexandre de Mendonça,Carolina Maruta,Mario Masellis,Sandra E. Black,Philippe Couratier,Géraldine Lautrette,Edward D. Huey,Sandro Sorbi,Benedetta Nacmias,Robert Laforce,Marie Pier L. Tremblay,Rik Vandenberghe,Philip Van Damme,Philip Van Damme,Emily Rogalski,Sandra Weintraub,Alexander Gerhard,Alexander Gerhard,Chiadi U. Onyike,Simon Ducharme,Sokratis G. Papageorgiou,Adeline Su Lyn Ng,Amy Brodtmann,Elizabeth Finger,Rita Guerreiro,Jose Bras,Jonathan D. Rohrer,Carolin Heller,Rhian S Convery,Ione O.C. Woollacott,Rachelle Shafei,Jonathan Graff-Radford,David T.W. Jones,Christina Dheel,Rodolfo Savica,Maria I. Lapid,Matt Baker,Julie A. Fields,Ralitza H. Gavrilova,Kimiko Domoto-Reilly,Jackie M. Poos,Emma L. van der Ende,Jessica L. Panman,Laura Donker Kaat,Harro Seelaar,Anna Richardson,Giovanni B. Frisoni,Anna Mega,Silvia Fostinelli,Huei Hsin Chiang,Antonella Alberici,Andrea Arighi,Chiara Fenoglio,Hilary W. Heuer,Bruce L. Miller,Anna Karydas,Jamie Fong,Maria João Leitão,Beatriz Santiago,Diana Duro,Carlos Ferreira,Alazne Gabilondo,Maria de Arriba,Mikel Tainta,Miren Zulaica,Catarina S. Ferreira,Elisa Semler,Albert C. Ludolph,Bernhard Landwehrmeyer,Alexander E Volk,Gabriel Miltenberger,Ana Verdelho,Sónia Afonso,Maria Carmela Tartaglia,Morris Freedman,Ekaterina Rogaeva,Camilla Ferrari,Irene Piaceri,Valentina Bessi,Gemma Lombardi,Frédéric St-Onge,Marie Claire Doré,Rose Bruffaerts,Mathieu Vandenbulcke,Jan Van den Stock,M.-Marsel Mesulam,Eileen H. Bigio,Christos Koros,John Papatriantafyllou,Christos Kroupis,Leonidas Stefanis,Christien Shoesmith,Erik Robertson,Giovanni Coppola,Eliana Marisa Ramos,Daniel H. Geschwind +177 more
TL;DR: An international study of age at symptom onset, age at death, and disease duration in individuals with mutations in GRN, MAPT, and C9orf72 to investigate the extent to which variability in age at onset and at death could be accounted for by family membership and the specific mutation carried.
Journal ArticleDOI
Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy
Naomi Kouri,Owen A. Ross,Beth A. Dombroski,Curtis S. Younkin,Daniel J. Serie,Alexandra I. Soto-Ortolaza,Matthew C. Baker,Ni Cole A. Finch,Hyejin Yoon,Jungsu Kim,Shinsuke Fujioka,Catriona McLean,Bernardino Ghetti,Salvatore Spina,Laura B. Cantwell,Martin R. Farlow,Jordan Grafman,Edward D. Huey,Mi Ryung Han,Sherry Beecher,Evan T. Geller,Hans A. Kretzschmar,Sigrun Roeber,Marla Gearing,Jorge L. Juncos,Jean Paul Vonsattel,Vivianna M. Van Deerlin,Murray Grossman,Howard I. Hurtig,Rachel Goldmann Gross,Steven E. Arnold,John Q. Trojanowski,Virginia M.-Y. Lee,Gregor K. Wenning,Charles L. White,Günter U. Höglinger,Günter U. Höglinger,Günter U. Höglinger,Ulrich Müller,Bernie Devlin,Lawrence I. Golbe,Julia E. Crook,Joseph E. Parisi,Bradley F. Boeve,Keith A. Josephs,Zbigniew K. Wszolek,Ryan J. Uitti,Neill R. Graff-Radford,Irene Litvan,Steven G. Younkin,Li-San Wang,Nilufer Ertekin-Taner,Rosa Rademakers,Hakon Hakonarsen,Gerard D. Schellenberg,Dennis W. Dickson +55 more
TL;DR: A genome-wide association study (GWAS) in CBD cases (n=152) and 3,311 controls, and 67 CBD cases and 439 controls in a replication stage was conducted in this article.