J
José Melo-Cristino
Researcher at Instituto de Medicina Molecular
Publications - 150
Citations - 5346
José Melo-Cristino is an academic researcher from Instituto de Medicina Molecular. The author has contributed to research in topics: Serotype & Multilocus sequence typing. The author has an hindex of 39, co-authored 139 publications receiving 4681 citations. Previous affiliations of José Melo-Cristino include University of Lisbon & Universidade Nova de Lisboa.
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Journal ArticleDOI
Rapid Inversion of the Prevalences of Macrolide Resistance Phenotypes Paralleled by a Diversification of T and emm Types among Streptococcus pyogenes in Portugal
TL;DR: In Portugal erythromycin resistance of 26.6% remained constant during 1998 to 2003, however in 1998 the MLSB phenotype dominated, whereas in 2003 the M phenotype prevailed.
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Increasing macrolide resistance among Streptococcus agalactiae causing invasive disease in non-pregnant adults was driven by a single capsular-transformed lineage, Portugal, 2009 to 2015.
Elísia Lopes,Tânia Fernandes,Miguel P. Machado,João A. Carriço,José Melo-Cristino,Mário Ramirez,E. R. Martins +6 more
TL;DR: Expansion of the new serotype Ib/CC1 lineage resulted in increased macrolide resistance in GBS, causing invasive disease among adults in Portugal and may predict more widespread increase in resistance.
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The autolysin LytA contributes to efficient bacteriophage progeny release in Streptococcus pneumoniae.
TL;DR: It is demonstrated that S. pneumoniae phages use the ubiquitous host autolysin to accomplish an optimal phage exiting strategy and that activation of bacterial LytA, together with the phage lysin, leads to greater phage progeny release.
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Superantigen gene complement of Streptococcus pyogenes—relationship with other typing methods and short-term stability
TL;DR: The results suggest that the SAg profile diversifies faster than other properties commonly used for molecular typing, such as emm type and multilocus sequence typing (MLST) sequence types (STs), and can be a useful complement in GAS molecular epidemiology.
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Case of aortic endocarditis caused by Lactobacillus casei
Líbia Zé-Zé,Rogério Tenreiro,A. Duarte,M. J. Salgado,José Melo-Cristino,L. Lito,M. M. Carmo,S. Felisberto,G. Carmo +8 more
TL;DR: A case of Lactobacillus aortic valve endocarditis in a 53-year-old immunocompetent patient with past history of rheumatic fever is reported.