J
José Melo-Cristino
Researcher at Instituto de Medicina Molecular
Publications - 150
Citations - 5346
José Melo-Cristino is an academic researcher from Instituto de Medicina Molecular. The author has contributed to research in topics: Serotype & Multilocus sequence typing. The author has an hindex of 39, co-authored 139 publications receiving 4681 citations. Previous affiliations of José Melo-Cristino include University of Lisbon & Universidade Nova de Lisboa.
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Journal ArticleDOI
Pherotype influences biofilm growth and recombination in Streptococcus pneumoniae.
Margarida Carrolo,Francisco R. Pinto,José Melo-Cristino,José Melo-Cristino,Mário Ramirez,Mário Ramirez +5 more
TL;DR: The influence of pherotype, defined by the two major comC allelic variants (comC1 and comC2), on biofilm development and recombination efficiency, was explored and suggested that strains carrying the comC1 allele may be more transmissible and more efficient at persisting in carriage.
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Changes in emm types and superantigen gene content of Streptococcus pyogenes causing invasive infections in Portugal.
TL;DR: There were no significant changes in the prevalence of individual emm types, emm clusters, or SAg profiles when comparing to 2006–2009, although an overall increasing trend was recorded during 2000–2015 for emm1, emn75, and emm87.
Journal ArticleDOI
The Viriato Study: update of antimicrobial susceptibility data of bacterial pathogens from community-acquired respiratory tract infections in Portugal in 2003 and 2004.
TL;DR: Of the 513 Streptococcus pyogenes strains isolated from patients with acute tonsillitis all were susceptible to penicillin and other beta-lactams but 18.9% were resistant to erythromycin, clarithromycin and azithromyc, and Penicillin was the most active antimicrobial agent against S. pyogene, H. influenza and M. catarrhalis.
Journal ArticleDOI
Distinct epidemiology and resistance mechanisms affecting ceftolozane/tazobactam in Pseudomonas aeruginosa isolates recovered from ICU patients in Spain and Portugal depicted by WGS.
Marta Hernández-García,María García-Castillo,Sergio García-Fernández,José Melo-Cristino,Margarida F Pinto,Elsa Gonçalves,Valquíria Alves,Ana Raquel Vieira,Elmano Ramalheira,Luísa Sancho,José Diogo,Rui Ferreira,Tânia F.C.V. Silva,Catarina Chaves,Germán Bou,Emilia Cercenado,Mercedes Delgado-Valverde,Antonio Oliver,Cristina Pitart,Jesús Rodríguez-Lozano,Nuria Tormo,João Romano,Leonor Pássaro,Laura Paixão,Diego López-Mendoza,Jazmín Díaz-Regañón,Rafael Cantón,Superior study groups +27 more
TL;DR: An extensive virulome was identified in all P. aeruginosa isolates, particularly in carbapenemase-producing strains, and ceftolozane/tazobactam resistance was significantly associated with GES-13 and VIM-type carbapanemase production.