J
José Melo-Cristino
Researcher at Instituto de Medicina Molecular
Publications - 150
Citations - 5346
José Melo-Cristino is an academic researcher from Instituto de Medicina Molecular. The author has contributed to research in topics: Serotype & Multilocus sequence typing. The author has an hindex of 39, co-authored 139 publications receiving 4681 citations. Previous affiliations of José Melo-Cristino include University of Lisbon & Universidade Nova de Lisboa.
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Journal ArticleDOI
Plasmid-Borne Antimicrobial Resistance of Staphylococcus aureus Isolated in a Hospital in Lisbon, Portugal
Sofia Santos Costa,Cláudia Palma,Kristina Kadlec,Andrea T. Fessler,Miguel Viveiros,José Melo-Cristino,Stefan Schwarz,Isabel Couto +7 more
TL;DR: The impact of plasmids on the resistance properties of S. aureus is demonstrated, highlighting their role in the dissemination of antibiotic, heavy metal, and biocide resistance genes, and survival of this major pathogen in the hospital environment.
Journal ArticleDOI
Avoiding Misdiagnosis of Imported Malaria: Screening of Emergency Department Samples with Thrombocytopenia Detects Clinically Unsuspected Cases
TL;DR: The blind screening of all thrombocytopenic samples with <100,000/microL by thick-blood film microscopy led to the diagnosis of 5 unsuspected malaria cases, which would have cost 21 hours of dedicated technician's time.
Journal ArticleDOI
Expanding the Diagnosis of Pediatric Bacteremic Pneumococcal Pneumonia from Blood Cultures to Molecular Methods: Advantages and Caveats
Mário Ramirez,José Melo-Cristino +1 more
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P1163 Emergence of optochin resistance among Streptococcus pneumoniae in Portugal
TL;DR: It is recommended that at least the bile solubility test should be routinely performed in cases of suspected pneumococcal etiology, even if the isolates are optochin-resistant, because accurate identification of S. pneumoniae is essential for correct diagnosis and adequate therapy of patients.
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Confronting Ceftolozane-Tazobactam Susceptibility in Multidrug-Resistant Enterobacterales Isolates and Whole-Genome Sequencing Results (STEP Study).
Marta Hernández-García,Sergio García-Fernández,María García-Castillo,José Melo-Cristino,Margarida F Pinto,Elsa Gonçalves,Valquíria Alves,Eliana Costa,Elmano Ramalheira,Luísa Sancho,José Diogo,Rui Ferreira,Tânia F.C.V. Silva,Catarina Chaves,Leonor Pássaro,Laura Paixão,João Romano,Rafael Cantón +17 more
TL;DR: WGS is a powerful tool for typing characterization and microbiological study of MDR-Enterobacterales pathogens and carbapenemase genes are associated with C/T-resistance in Klebsiella spp.