J
José Melo-Cristino
Researcher at Instituto de Medicina Molecular
Publications - 150
Citations - 5346
José Melo-Cristino is an academic researcher from Instituto de Medicina Molecular. The author has contributed to research in topics: Serotype & Multilocus sequence typing. The author has an hindex of 39, co-authored 139 publications receiving 4681 citations. Previous affiliations of José Melo-Cristino include University of Lisbon & Universidade Nova de Lisboa.
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Journal ArticleDOI
Methaemoglobin and COHb in patients with malaria
Thomas Hänscheid,Tom M Gresnigt,Sascha J Z Löhr,Arnaud Flamen,Thomas Zoller,José Melo-Cristino,Martin P. Grobusch +6 more
TL;DR: The data appears consistent with the methaemoglobin/haem hypothesis in malaria and sepsis pathogenesis, however, although MetHb was significantly different between healthy controls and children with malaria in Africa, the difference was rather small, also when compared to previous studies.
Journal ArticleDOI
Use of the 13-valent conjugate vaccine has the potential to eliminate pilus carrying isolates as causes of invasive pneumococcal disease
TL;DR: The overall proportion of piliated isolates declined in the period following PCV7 but quickly recovered to pre-PCV7 levels (50%) and the proportion of isolates carrying both pilus islands remained stable and low.
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Identification of immunoreactive extracellular proteins of Streptococcus agalactiae in bovine mastitis.
Gabriela Trigo,Paula Ferreira,Niza RibeiroN. Ribeiro,Márcia Dinis,Elva Bonifácio Andrade,José Melo-Cristino,Mário Ramirez,Delfina Tavares +7 more
TL;DR: Group B protective surface protein and 5'-nucleotidase family protein were 2 major immunoreactive proteins that were detected only in the whey of infected cows, suggesting that these proteins may be important in the pathogenesis of S. agalactiae-induced mastitis.
Posted ContentDOI
Seroprevalence of anti-SARS-CoV-2 antibodies in COVID-19 patients and healthy volunteers
Patrícia Figueiredo-Campos,Birte Blankenhaus,Catarina Mota,Andreia Gomes,Marta Serrano,Silvia Ariotti,Catarina Costa,Helena Nunes-Cabaço,António M. Mendes,Pedro Gaspar,Pereira-Santos Cm,Filipe B. Rodrigues,Jorge Condeço,Escoval Am,Maria José Santos,Mário Ramirez,José Melo-Cristino,Simas Pj,Simas Pj,Eugenia Vasconcelos,A. Afonso,Marc Veldhoen +21 more
TL;DR: This work quantified immunoglobulin M, IgG and IgA antibodies recognizing the SARS-CoV-2 receptor-binding domain (RBD) or the Spike (S) protein over a period of five months following COVID-19 disease onset or in previously Sars-Cov-2 PCR-positive volunteers, and highlighted a continued level of circulating neutralising antibodies in most people with confirmed SARS, at least up to five months after infection.
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Invasive Pneumococcal Disease in Adults in Portugal: The Importance of Serotypes 8 and 3 (2015-2018).
TL;DR: In this article, the authors characterized 2172 cases of adult IPD in 2015-2018 in Portugal after the introduction of pneumococcal conjugate vaccine (PCV13) in the national immunization plan of 2015.