José Melo-Cristino

TL;DR: The characterization of group A streptococci recovered during 2004-2006 revealed that resistance was not stable during this period and that the decline in erythromycin resistance observed during2004-2006 was due to a decrease in the prevalence of isolates presenting the M phenotype, while the proportion of isolate expressing the MLS(B) phenotype remained stable.

TL;DR: Staphylococci can contribute to persistence and severity of diabetic foot infections, leading to treatment failure and to the possibility of transmitting these features to other microorganisms sharing the same niche, as well as present resistance to medically important antibiotics and harbour virulence determinants.

TL;DR: A seasonal rise in severity of IGASI suggested that generalised seasonal increase in host susceptibility, rather than introduction of more virulent strains may play a role in the pathogenesis of these potentially fatal infections.

TL;DR: Despite the absence of VRSA dissemination, the recent increase in the incidence of lineages belonging to CC5 in some European countries, including Portugal, may result in more frequent opportunities for the emergence ofVRSA.

TL;DR: The results obtained in this work do not exclude the importance of mutations in resistance to fluoroquinolones in S. aureus, yet they underline the contribution of efflux systems for the emergence of high-level resistance.