Joseph R. Hibbeln

TL;DR: Risks from the loss of nutrients were greater than the risks of harm from exposure to trace contaminants in 340 g seafood eaten weekly, suggesting that advice to limit seafood consumption could actually be detrimental.

TL;DR: The hypothesis that a high consumption of fish could be correlated with a lower annual prevalence of major depression was tested and the direction and power of the correlation between apparent fish consumption and major depression did not show that fish consumption can cause differences in the prevalence ofmajor depression or that eating fish or fish oils are useful in treatment.

TL;DR: The apparent increased consumption of LA, which was primarily from soybean oil, has likely decreased tissue concentrations of EPA and DHA during the 20th century.

TL;DR: The preponderance of epidemiologic and tissue compositional studies supports a protective effect of omega-3 EFA intake, particularly eicosapentaenoic acid (EPA) and docosahexaenoic Acid (DHA), in mood disorders.

TL;DR: The inefficiency of the conversion of 18:3n-3 to 20:5n- 3 indicates that the biosynthesis of long-chain n-3 PUFA from alpha-linolenic acid is limited in healthy individuals, and the much greater rate of transfer of mass from the plasma 20: 5n-4 compartment to 22:5N-3 suggests that dietary eicosapentaenoic acid may be well utilized in the biosynthetic of 22:6n-