J
Joseph Ragaz
Researcher at University of British Columbia
Publications - 56
Citations - 17057
Joseph Ragaz is an academic researcher from University of British Columbia. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 23, co-authored 55 publications receiving 16021 citations. Previous affiliations of Joseph Ragaz include McGill University & University of Toronto.
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Journal ArticleDOI
Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials
O. Abe,R. Abe,K. Enomoto,K. Kikuchi,H. Koyama,H. Masuda,Y. Nomura,K. Sakai,K. Sugimachi,T. Tominaga,J. Uchino,M. Yoshida,J. L. Haybittle,C Davies,V. J. Harvey,T. M. Holdaway,R. G. Kay,B. H. Mason,John F. Forbes,Nicholas Wilcken,M. Gnant,Raimund Jakesz,M. Ploner,H. M. A. Yosef,C. Focan,J. P. Lobelle,U. Peek,G. D. Oates,Janet T. Powell,M. Durand,L. Mauriac,A. Di Leo,Stella Dolci,M.J. Piccart,M. B. Masood,D. Parker,J. J. Price,Pierre Hupperets,Sue Jackson,Joseph Ragaz,Donna L. Berry,Gloria Broadwater,C. Cirrincione,Hyman B. Muss,Larry Norton,Raymond B. Weiss,H. Abu-Zahra,S. M. Portnoj,Michael J. Baum,Jack Cuzick,Joan Houghton,David Riley,N. H. Gordon,H. L. Davis,A. Beatrice,J. Mihura,A. Naja,Y. Lehingue,P. Romestaing,J. B. Dubois,Thierry Delozier,J. Mace-Lesec'h,P. Rambert,O. Andrysek,J. Barkmanova,Julie Owen,P. Meier,A Howell,G. C. Ribeiro,R. Swindell,R Alison,J Boreham,Matthew Clarke,Rory Collins,Sarah C. Darby,P. Elphinstone,Vaughan Evans,Jon Godwin,Richard Gray,C. S. Harwood,C. Hicks,Spencer L. James,Elizabeth MacKinnon,Paul McGale,Theresa McHugh,Graham M. Mead,Richard Peto,Yisong Wang,J. Albano,C. F. de Oliveira,H. Gervasio,J. Gordilho,H Johansen,Henning T. Mouridsen,Rebecca Gelman,J.R. Harris,I. C. Henderson,Charles L. Shapiro,K. W. Andersen,C. K. Axelsson,M. Blichert-Toft,S. Moller,Jens Overgaard,Marie Overgaard,Carsten Rose,B. Cartensen,T. Palshof,H. J. Trampisch,Otilia Dalesio,E.G.E. de Vries,Sjoerd Rodenhuis,H. van Tinteren,R. L. Comis,Nancy E. Davidson,Nicholas J. Robert,George W. Sledge,Douglass C. Tormey,William C. Wood,David Cameron,Udi Chetty,P. Forrest,W. Jack,J. Rossbach,Jan G. M. Klijn,A. D. Treurniet-Donker,W. L. J. van Putten,Alberto Costa,Umberto Veronesi,H. Bartelink,L. Duchateau,C. Legrand,RJ Sylvester,J.A. van der Hage,C.J.H. van de Velde,M. P. Cunningham,R. Catalano,R. H. Creech,Jacques Bonneterre,P. Fargeot,Pierre Fumoleau,Pierre Kerbrat,Moïse Namer,Walter Jonat,Manfred Kaufmann,Martin Schumacher,G. von Minckwitz,G. Bastert,H. Rauschecker,R. Sauer,Willi Sauerbrei,A.J. Schauer,A. de Schryver,L. Vakaet,M. Belfiglio,A. Nicolucci,F. Pellegrini,M. Sacco,M. Valentini,C. S. McArdle,D. C. Smith,E. Galligioni,Francesco Boccardo,AU Rubagotti,D. M. Dent,C. A. Gudgeon,A. Hacking,A. Erazo,J. Y. Medina,M. Izuo,Y. Morishita,H. Takei,I.S. Fentiman,John L. Hayward,R D Rubens,D. Skilton,H. Graeff,Fritz Jänicke,C. Meisner,H. R. Scheurlen,D. von Fournier,Urania Dafni,G. Fountzilas,P. Klefstrom,Carl Blomqvist,T. Saarto,R. Margreiter,Bernard Asselain,R. J. Salmon,J. R. Vilcoq,Rodrigo Arriagada,Christopher Hill,A. Laplanche,M. G. Le,M. Spielmann,Paolo Bruzzi,E. Montanaro,R. Rosso,M. R. Sertoli,M. Venturini,Dino Amadori,J. Benraadt,M. Kooi,A. O. van de Velde,J. A. van Dongen,J. B. Vermorken,Monica Castiglione,F. Cavalli,A. S. Coates,J. Collins,JF Forbes,Richard D. Gelber,A. Goldhirsch,J. Lindtner,Karen N. Price,C. M. Rudenstam,H.-J. Senn,Judith M Bliss,Clair Chilvers,R. C. Coombes,Emma Hall,Michel Marty,R. V. Borovik,G. Brufman,H. Hayat,E. Robinson,N. Wigler,Gianni Bonadonna,T. Camerini,G. De Palo,M. Del Vecchio,F. Formelli,Pinuccia Valagussa,A Martoni,F. Pannuti,G. Cocconi,A. Colozza,R. Camisa,K. Aogi,S. Takashima,T. Ikeda,K. Inokuchi,K. Sawa,H. Sonoo,S. Korzeniowski,J. Skolyszewski,M. Ogawa,J. Yamashita,J. Bonte,R. Christiaens,Robert Paridaens,W. Van den Boegart,P. Martin,S. Romain,T. Hakes,Clifford A. Hudis,R. Wittes,G. Giokas,D. Kondylis,B. Lissaios,R. de la Huerta,M. G. Sainz,R. Altemus,K. Cowan,David N. Danforth,Allen S. Lichter,Marc E. Lippman,Joyce A. O'Shaughnessy,Lori J. Pierce,Seth M. Steinberg,D. Venzon,JoAnne Zujewski,A. Paradiso,M. De Lena,F. Schittulli,J. Myles,J. L. Pater,Kathleen I. Pritchard,Stewart J. Anderson,G. Bass,Anna Brown,John Bryant,J. Costantino,James J. Dignam,Bernard Fisher,C Redmond,Sam Wieand,Norman Wolmark,I. M. Jackson,Mike K. Palmer,JN Ingle,Vera J. Suman,Nils-Olof Bengtsson,H. Jonsson,Lars-Gunnar Larsson,J. P. Lythgoe,M. Kissin,Bjørn Erikstein,E Hannisdal,A. B. Jacobsen,J. E. Varhaug,S. Gundersen,Martin Hauer-Jensen,H. Host,R. Nissen-Meyer,Roger W. Blamey,A. Mitchell,Morgan Da,J.F.R. Robertson,M. Di Palma,G. Mathe,J. L. Misset,R. M. Clark,Mitch Levine,K Morimoto,Y. Takatsuka,E. Crossley,Al Harris,Denis Talbot,Mark Taylor,B. di Blasio,V. Ivanov,Vladimir Semiglazov,J. Brockschmidt,M. R. Cooper,H. Ueo,Carla I. Falkson,Roger A'Hern,Stanley W. Ashley,T. J. Powles,Ian E. Smith,John Yarnold,J.-C. Gazet,N. Cocoran,N. Deshpande,L. di Martino,P. Douglas,A. Lindtner,G Notter,A. J. S. Bryant,G. H. Ewing,L. A. Firth,J. L. Krushen-Kosloski,L. Foster,W.D. George,Helen J. Stewart,P. Stroner,Per-Uno Malmström,Torgil Möller,Stefan Rydén,Ingrid Tengrup,Lena Tennvall-Nittby,J. Carstenssen,M. Dufmats,Thomas Hatschek,Bo Nordenskjöld,Martin Söderberg,John T. Carpenter,KS Albain,J. Crowley,Stuart A. Green,Silvana Martino,CK Osborne,Peter M. Ravdin,U. Glas,Ulla Johansson,L E Rutqvist,T. Singnomklao,Arne Wallgren,Rudolf Maibach,Beat Thürlimann,Hermann Brenner,A. Hercbergs,M Yoshimoto,Gerrit DeBoer,Alexander H.G. Paterson,JW Meakin,T. Panzarella,Y. Shan,Y. F. Shao,X. Wang,D. B. Zhao,Z. M. Chen,H. C. Pan,J. Bahi,M. Reid,M. Spittle,G. P. Deutsch,F. Senanayake,D. L. W. Kwong,Angelo Raffaele Bianco,Chiara Carlomagno,M. De Laurentiis,S. De Placido,Aman U. Buzdar,Tae C Smith,Jonas Bergh,Lars Holmberg,Göran Liljegren,Jan Nilsson,M. Seifert,P. Sevelda,C. C. Zielinsky,R. B. Buchanan,M. Cross,G.T. Royle,Janet A. Dunn,Robert Kerrin Hills,Michael Lee,J. M. Morrison,D. Spooner,A. Litton,Rowan T. Chlebowski,H. Caffier +412 more
TL;DR: The 10-year and 15-year effects of various systemic adjuvant therapies on breast cancer recurrence and survival are reported and it is found that the cumulative reduction in mortality is more than twice as big at 15 years as at 5 years after diagnosis.
Journal Article
Polychemotherapy for early breast cancer: an overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group.
C. Focan,Seth M. Steinberg,M. Blichert-Toft,JF Forbes,Rory Collins,Stewart J. Anderson,R. Margreiter,C. S. Harwood,K. W. Andersen,G. Beighton,R. V. Borovik,EA Clarke,T Yasutomi,Walter Jonat,E. Mari,O. Abe,Richard Peto,Richard Gray,J. B. Vermorken,Bernard Asselain,Mitchell A Harris,Ingrid Tengrup,PC Lara,J.L. Laplanche,Sue Jackson,RJ Sylvester,H. Ueo,Pierre Fumoleau,R. Sauer,William C. Wood,Willi Sauerbrei,Rebecca Gelman,J. C. Redmond,Angelo Raffaele Bianco,Rodrigo Arriagada,M Hauer,Marie Overgaard,M. P. Cunningham,John L. Hayward,M. Kissin,Owen,W. Jack,Cooper,J. L. Pater,M. Ogawa,Jon Godwin,N Scorpiglione,Mike K. Palmer,H Johansen,H. Hayat,Aman U. Buzdar,Hyman B. Muss,H. Sonoo,David Riley,G. Brufman,MJ Piccart-Gebhart,John Bryant,R. Nissen,H. Koyama,J. Uchino,D. Parker,J Mace,M. Durand,G. Cocconi,Y. Morishita,CF Oliveira,R. L. Comis,A. Goldhirsch,M. Spielmann,J. E. Varhaug,Carsten Rose,J-B Bonte,A. R. Coates,C. S. McArdle,J. J. Price,Janet T. Powell,L. M. Vecchio,Martin Schumacher,Matthew Clarke,A. Nicolucci,Larry Norton,G. Mathe,H.H. Tooth,R. Huerta,A. Erazo Velásquez,Norman Wolmark,N. H. Gordon,Joan Houghton,Michael J. Baum,S. Gundersen,R. H. Creech,Gianni Bonadonna,D. C. Smith,R. J. Salmon,D.F. Hacking,R. C. Coombes,Kathleen I. Pritchard,Y. Lehingue,James J. Dignam,L. Mauriac,J. Myles,Sam Wieand,Spencer L. James,Carla I. Falkson,Carl Blomqvist,M. Belfiglio,H. L. Davis,AU Rubagotti,V. Gouon-Evans,K. Sawa,F. Pannuti,Francesco Boccardo,R. Abe,I.S. Fentiman,K. Sakai,T. M. Holdaway,Gloria Broadwater,Pinuccia Valagussa,M. G. Le,J. B. Dubois,Tae C Smith,J. Collins,M. Izuo,Manfred Kaufmann,C. K. Axelsson,Nancy E. Davidson,R Simon,AO de Lima,J. Yamashita,H. J. Trampisch,Jack Cuzick,S. Takashima,E. Robinson,G. Fountzilas,Lippman amp,Donna L. Berry,Henning T. Mouridsen,R. Wittes,A Kodric-Brown,R. M. Clark,D Jackson,N Corcoran,Umberto Veronesi,D. M. Dent,K Morimoto,C Davies,Y. Takatsuka,B Carstensen,Bernard Fisher,Lars-Gunnar Larsson,Cjh van de Velde,E. F. Lau,E. Greaves,P. Meier,Roger W. Blamey,John F. Forbes,Hma Yosef,R. Swindell,G. Bastert,Moïse Namer,JN Ingle,J. L. Misset,R. G. Kay,J. Benraadt,Christopher Hill,S. Romain,J. L. Haybittle,Karen N. Price,N. Wigler,R. Catalano,Judith M Bliss,Jfr Robertson,Lori J. Pierce,Vera J. Suman,Monica Castiglione,R D Rubens,H. Host,J. Albano,K. Kikuchi,A.J. Schauer,B. H. Mason,A Lewit-Bentley,Thierry Delozier,H.-J. Senn,Vilcoq,B Dil Blasio,T. Hakes,Douglass C. Tormey,J. Skolyszewski,K Welvaart,T. Tominaga,C. M. Rudenstam,JA Dongen,J. Costantino,S Bartholomeus,G. C. Mead,Michel Marty,Richard D. Gelber,M. Yoshida,McLaughlin,Mitch Levine,Joseph Ragaz,K. Enomoto,D Fournier,SB Schryver,V. J. Harvey,Udi Chetty,Y. Nomura,J. Lindtner,P. Forrest,N Cole Robert,Jacques Bonneterre,J. P. Lobelle,A. Bengry-Howell,P. Romestaing,I. C. Henderson,P Martin-Sanz,T. Palshof,G. C. Ribeiro,E Hannisdal,A. H. Gervasio,K. Sugimachi,Charles L. Shapiro,R. E. Crossley,C. Cirrincione,I. M. Jackson,Michael Gnant +226 more
TL;DR: The age-specific benefits of polychemotherapy appeared to be largely irrespective of menopausal status at presentation, oestrogen receptor status of the primary tumour, and of whether adjuvant tamoxifen had been given.
Journal ArticleDOI
Immunohistochemical and Clinical Characterization of the Basal-Like Subtype of Invasive Breast Carcinoma
Torsten O. Nielsen,Forrest D. Hsu,Kristin C. Jensen,Maggie C.U. Cheang,Gamze Karaca,Zhiyuan Hu,Tina Hernandez-Boussard,Chad A. Livasy,Dave Cowan,Lynn G. Dressler,Lars A. Akslen,Joseph Ragaz,Allen M. Gown,C. Blake Gilks,Matt van de Rijn,Charles M. Perou +15 more
TL;DR: A panel of four antibodies (ER, HER1, HER2, and cytokeratin 5/6) can accurately identify basal-like tumors using standard available clinical tools and shows high specificity.
Journal ArticleDOI
Adjuvant Radiotherapy and Chemotherapy in Node-Positive Premenopausal Women with Breast Cancer
Joseph Ragaz,Stewart M. Jackson,Nhu D. Le,Ian H. Plenderleith,John J. Spinelli,Vivian E. Basco,Kenneth S. Wilson,Margaret A. Knowling,Christopher M.L. Coppin,Marilyn Paradis,Andrew J. Coldman,Ivo A. Olivotto +11 more
TL;DR: Radiotherapy combined with chemotherapy after modified radical mastectomy decreases rates of locoregional and systemic relapse and reduces mortality from breast cancer.
Journal ArticleDOI
Locoregional Radiation Therapy in Patients With High-Risk Breast Cancer Receiving Adjuvant Chemotherapy: 20-Year Results of the British Columbia Randomized Trial
Joseph Ragaz,Ivo A. Olivotto,John J. Spinelli,Norman Phillips,Stewart M. Jackson,Kenneth S. Wilson,Margaret A. Knowling,Christopher M.L. Coppin,Lorna Weir,Karen A. Gelmon,Nhu D. Le,Ralph E. Durand,Andrew J. Coldman,Mohamed Manji +13 more
TL;DR: For patients with high-risk breast cancer treated with modified radical mastectomy, treatment with radiation therapy and adjuvant chemotherapy leads to better survival outcomes than chemotherapy alone, and it is well tolerated, with acceptable long-term toxicity.