J
Judite Costa
Researcher at University of Lisbon
Publications - 43
Citations - 951
Judite Costa is an academic researcher from University of Lisbon. The author has contributed to research in topics: Protonation & Metal ions in aqueous solution. The author has an hindex of 19, co-authored 43 publications receiving 861 citations. Previous affiliations of Judite Costa include University of Nebraska–Lincoln & Instituto Superior Técnico.
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Journal ArticleDOI
Metal complexes of macrocyclic ligands containing pyridine
Judite Costa,Rita Delgado +1 more
TL;DR: Some macrocyclic compounds containing pyridinc have been synthetized: 3,6,9,15-tetraazabicyclo[9.3.1]hexadeca-1(16),12,14-triene(2), 3,7,11,17-TTEBICCLO[11.3 as mentioned in this paper, 13,15 trienc (4).
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Dissociation constants of Br∅nsted acids in D2O and H2O: studies on polyaza and polyoxa-polyaza macrocycles and a general correlation
TL;DR: In this article, a linear correlation between the dissociation constants of polyaza and polyoxa-polyaza macrocyclic compounds was established between the acid forms obtained in deuterium oxide (p K D ) and in water ( p K H ).
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Macrocyclic copper(II) complexes: Superoxide scavenging activity, structural studies and cytotoxicity evaluation
Ana Sofia Fernandes,Jorge Gaspar,M. Fátima Cabral,Cátia Caneiras,Rita C. Guedes,José Rueff,Matilde Castro,Judite Costa,Nuno G. Oliveira +8 more
TL;DR: Five macrocyclic copper(II) complexes are synthesized and evaluated their ability to scavenge the superoxide anions generated by the xanthine-xanthine oxidase system, finding some of the presented complexes appear to be promising superoxide scavenger agents, and should be considered for further biological assays.
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13- and 14-membered macrocyclic ligands containing methylcarboxylate or methylphosphonate pendant arms: Chemical and biological evaluation of their 153Sm and 166Ho complexes as potential agents for therapy or bone pain palliation
Fernanda Marques,Lurdes Gano,M. Paula C. Campello,Sara Lacerda,Isabel Santos,Luís M. P. Lima,Judite Costa,Patricia Antunes,Rita Delgado +8 more
TL;DR: Biodistribution studies in mice demonstrated that (153)Sm/(166)Ho-trita complexes have a fast tissue clearance with more than 95% of the injected activity excreted after 2 h, value that is comparable to the corresponding dota complexes, in contrast, the ( 153)Sm-teta complex has a significantly lower total excretion.
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Lanthanide complexes of macrocyclic derivatives useful for medical applications
TL;DR: In this paper, the protonation constants of two series of tetraazamacrocyclic ligands with acetate and methylphosphonate pendant arms, as well as their stability constants with Cu 2+, La 3+, Sm 3+ and Ho 3+ were determined.