Julia Alles

TL;DR: The experimentally validated miRNAs will contribute to revising targetomes hypothesized by utilizing falsely annotated miRNA candidates, 1115 of which are currently annotated in miRBase V22.

TL;DR: The data suggest that the mutations in miR‐142 probably lead to a loss rather than a gain of function, which is the first report describing mutations of a miRNA gene in a large percentage of a distinct lymphoma subtype.

TL;DR: The relevance of deregulated miRNAs for the post-transcriptional gene regulation in nasal NK/T-cell lymphomas is demonstrated and the targets were confirmed by reporter assays and by down-regulation of the proteins by ectopic expression of the cognate miRN

TL;DR: It is determined that 0.8% of the human genome are reliably covered by 874 123 regions with an average length of 31 nt, and among the known small non‐coding RNA classes, microRNAs were the most prevalent.

TL;DR: This study establishes a link between up-regulation of miR-23a/b-3p and the coincident down- regulation of four expressed genes in the sperm of men with oligoasthenozoospermic men, compared with men with normozoospermia.