J
Julia Schüler
Researcher at University of Konstanz
Publications - 119
Citations - 4331
Julia Schüler is an academic researcher from University of Konstanz. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 28, co-authored 96 publications receiving 3659 citations. Previous affiliations of Julia Schüler include University of Bern & University of Zurich.
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The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
Ulrich F. Wellner,Jörg Schubert,Ulrike Burk,Otto Schmalhofer,Feng Zhu,Annika G Sonntag,Bettina Waldvogel,Corinne Vannier,Douglas S. Darling,Axel zur Hausen,Valerie G. Brunton,Jennifer P. Morton,Owen J. Sansom,Julia Schüler,Marc P. Stemmler,Christoph Herzberger,Ulrich T. Hopt,Tobias Keck,Simone Brabletz,Thomas Brabletz +19 more
TL;DR: It is proposed that ZEB1 links EMT-activation and stemness-maintenance by suppressingstemness-inhibiting microRNAs (miRNAs) and thereby is a promoter of mobile, migrating cancer stem cells.
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ZEB1-associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat
Simone Meidhof,Simone Brabletz,Waltraut Lehmann,Bogdan-Tiberius Preca,Kerstin Mock,Manuel Ruh,Julia Schüler,Maria Berthold,Anika Weber,Ulrike Burk,Michael Lübbert,Michael Lübbert,Martin Puhr,Zoran Culig,Ulrich F. Wellner,Tobias Keck,Peter Bronsert,Simon Küsters,Ulrich T. Hopt,Marc P. Stemmler,Thomas Brabletz,Thomas Brabletz +21 more
TL;DR: The data encourage the application of mechanism‐based combinations of selected epigenetic drugs with standard chemotherapy for the rational treatment of aggressive solid tumors, such as pancreatic cancer.
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Wanting, having, and needing : Integrating motive disposition theory and self-determination theory
Kennon M. Sheldon,Julia Schüler +1 more
TL;DR: Four studies explored the motivational and experiential dynamics of psychological needs, applying both self-determination theory and motive disposition theory, finding that motive dispositions toward achievement and affiliation predicted corresponding feelings of competence and relatedness, which predicted well-being.
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Action crisis and cost–benefit thinking: A cognitive analysis of a goal-disengagement phase
TL;DR: Gollwitzer et al. as mentioned in this paper found that participants who were experiencing an action crisis in such diverse goal areas as intimate relationships, sports, and university studies, thought about goal-related costs and benefits more intensively and frequently in comparison to participants who did not experience action crisis, and they recognized more of cost-benefit-items and less of implementation-items than the control group.
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Implicit need for achievement moderates the relationship between competence need satisfaction and subsequent motivation
TL;DR: In this article, a cross-sectional and a longitudinal study showed that felt competence in a sports activity has especially positive effects on subsequent flow and intrinsic motivation for individuals high in the need for achievement.