J
Julie E. J. Nixon
Researcher at Harvard University
Publications - 6
Citations - 1324
Julie E. J. Nixon is an academic researcher from Harvard University. The author has contributed to research in topics: Giardia lamblia & Gene. The author has an hindex of 6, co-authored 6 publications receiving 1273 citations. Previous affiliations of Julie E. J. Nixon include Marine Biological Laboratory.
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Journal ArticleDOI
Genomic minimalism in the early diverging intestinal parasite Giardia lamblia.
Hilary G. Morrison,Andrew G. McArthur,Frances D. Gillin,Stephen B. Aley,Rodney D. Adam,Gary J. Olsen,Aaron A. Best,W. Zacheus Cande,Feng Chen,Michael J. Cipriano,Barbara J. Davids,Scott C. Dawson,Heidi G. Elmendorf,Adrian B. Hehl,Michael Holder,Susan M. Huse,Ulandt Kim,Erica Lasek-Nesselquist,Gerard Manning,Anuranjini Nigam,Julie E. J. Nixon,Daniel Palm,Nora Q.E. Passamaneck,Anjali Prabhu,Claudia I. Reich,David S. Reiner,John Samuelson,Staffan G. Svärd,Mitchell L. Sogin +28 more
TL;DR: The genome of the eukaryotic protist Giardia lamblia, an important human intestinal parasite, is compact in structure and content, contains few introns or mitochondrial relics, and has simplified machinery for DNA replication, transcription, RNA processing, and most metabolic pathways.
Journal ArticleDOI
The Giardia genome project database
Andrew G. McArthur,Hilary G. Morrison,Julie E. J. Nixon,Nora Q.E. Passamaneck,Ulandt Kim,Gregory Hinkle,Melissa K. Crocker,Michael Holder,Rebecca Farr,Claudia I. Reich,Gary E. Olsen,Stephen B. Aley,Rodney D. Adam,Frances D. Gillin,Mitchell L. Sogin +14 more
TL;DR: The Giardia genome project database provides an online resource forGiardia lamblia (WB strain, clone C6) genome sequence information, which includes edited single-pass reads, the results of BLASTX searches, and details of progress towards sequencing the entire 12 million-bp Giardian genome.
Journal ArticleDOI
A spliceosomal intron in Giardia lamblia.
Julie E. J. Nixon,Amy J. Wang,Hilary G. Morrison,Andrew G. McArthur,Mitchell L. Sogin,Brendan J. Loftus,John Samuelson +6 more
TL;DR: Phylogenetic analyses show the Giardia Sm core peptides are the products of multiple, ancestral gene duplications followed by divergence, but they retain strong similarity to Sm and like-Sm peptides of other eukaryotes.
Journal ArticleDOI
Evidence for Lateral Transfer of Genes Encoding Ferredoxins, Nitroreductases, NADH Oxidase, and Alcohol Dehydrogenase 3 from Anaerobic Prokaryotes to Giardia lamblia and Entamoeba histolytica
Julie E. J. Nixon,Amy J. Wang,Jessica Field,Hilary G. Morrison,Andrew G. McArthur,Mitchell L. Sogin,Brendan J. Loftus,John Samuelson +7 more
TL;DR: Although there were not enough sequences to perform meaningful phylogenetic analyses, the unique common occurrence of these peptides and enzymes in giardia organisms, amebae, and the few anaerobic prokaryotes suggests the possibility of lateral transfer.
Journal ArticleDOI
Iron-dependent hydrogenases of Entamoeba histolytica and Giardia lamblia: activity of the recombinant entamoebic enzyme and evidence for lateral gene transfer.
Julie E. J. Nixon,Jessica Field,Andrew G. McArthur,Mitchell L. Sogin,Nigel Yarlett,Brendan J. Loftus,John Samuelson +6 more
TL;DR: Phylogenetic analyses suggested that the short Fe-hydrogenase genes of entamoeba and diplomonads share a common ancestor, while the long Fe-Hydrogenase gene of entamaeba appears to have been laterally transferred from a bacterium.