J
Jun He
Researcher at Tianjin University of Traditional Chinese Medicine
Publications - 99
Citations - 2805
Jun He is an academic researcher from Tianjin University of Traditional Chinese Medicine. The author has contributed to research in topics: High-performance liquid chromatography & Cancer. The author has an hindex of 24, co-authored 96 publications receiving 2090 citations. Previous affiliations of Jun He include Thomas Jefferson University & Nanjing Medical University.
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Thrombin-based discovery strategy of bioactive-chemical quality marker combination for pollen of Typha orientalis by metabolomics coupled with chemometrics.
Xiaoyan Wang,Xuanhao Chen,Jin Li,Owusu Boadi Evans,Hui Wang,Xuejing Yang,Jun He,Xiumei Gao,Yan-xu Chang +8 more
TL;DR: The thrombin-based discovery strategy of bioactive-chemical marker combination was a powerful tool for screening the quality markers for evaluation of pollen of T. orientalis.
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An Improved LC-MS/MS Method for Simultaneous Determination of the Eleven Bioactive Constituents for Quality Control of Radix Angelicae Pubescentis and Its Related Preparations
TL;DR: An improved LC-MS/MS method was developed for simultaneous determination of eleven bioactive constituents of Radix Angelicae Pubescentis and its related preparations and showed good regression within test ranges and the recoveries were in the range of 87.1–110%.
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Influence of different processing times on the quality of Polygoni Multiflora Radix by metabolomics based on ultra high performance liquid chromatography with quadrupole time-of-flight mass spectrometry.
TL;DR: The results demonstrated that the metabolomics method could provide scientific support for the processing standardization of Polygoni Multiflora Radix.
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A validated LC–MS/MS assay for the simultaneous determination of periplocin and its two metabolites, periplocymarin and periplogenin in rat plasma: Application to a pharmacokinetic study
Jun He,Fang Bo,Yaru Tu,John Teye Azietaku,Ting Dou,Huizi Ouyang,Yan-xu Chang,Hong Liu,Xiumei Gao +8 more
TL;DR: A sensitive and reliable LC-MS/MS method was developed and validated for the simultaneous determination of periplocin and its two metabolites (periplocymarin and periplogenin) in rat plasma using psoralen as the internal standard (IS) and was successfully applied to evaluating the pharmacokinetic studies in rats.
Journal ArticleDOI
Reactive oxygen species reprogram macrophages to suppress antitumor immune response through the exosomal miR-155-5p/PD-L1 pathway
Xiang Li,Shaomin Wang,Wei Mu,Jennifer Barry,Anna Frances Han,Richard L. Carpenter,Bing-Hua Jiang,Stephen C. Peiper,My G. Mahoney,Andrew E. Aplin,Hong Ren,Jun He +11 more
TL;DR: In this article , the role of exosomal miR-155-5p in tumor growth was evaluated in xenograft nude mice models and immune-competent mice models.