J
Jun He
Researcher at Tianjin University of Traditional Chinese Medicine
Publications - 99
Citations - 2805
Jun He is an academic researcher from Tianjin University of Traditional Chinese Medicine. The author has contributed to research in topics: High-performance liquid chromatography & Cancer. The author has an hindex of 24, co-authored 96 publications receiving 2090 citations. Previous affiliations of Jun He include Thomas Jefferson University & Nanjing Medical University.
Papers
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Journal ArticleDOI
NADPH oxidase subunit p22(phox)-mediated reactive oxygen species contribute to angiogenesis and tumor growth through AKT and ERK1/2 signaling pathways in prostate cancer.
Qi Li,Guang Bo Fu,Ji Tai Zheng,Jun He,Xiao Bing Niu,Qiu Dan Chen,Yu Yin,Xu Qian,Qing Xu,Min Wang,An Fang Sun,Yongqian Shu,Hallgeir Rui,Ling-Zhi Liu,Bing-Hua Jiang +14 more
TL;DR: Findings reveal a new function of p22(phox) in tumor angiogenesis and tumor growth, and suggest that p 22( phox) is a potential novel target for prostate cancer treatment.
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Oral Administration of Apigenin Inhibits Metastasis through AKT/P70S6K1/MMP-9 Pathway in Orthotopic Ovarian Tumor Model
Jun He,Qing Xu,Min Wang,Chongyong Li,Xu Qian,Zhumei Shi,Ling-Zhi Liu,Bing-Hua Jiang,Bing-Hua Jiang +8 more
TL;DR: In this paper, the effect of apigenin via oral administration on tumor growth and metastasis remains unknown, however, the authors developed an orthotopic ovarian tumor model in nude mice and showed that apigenins inhibited the micrometastasis of cancer cells in the animal tumor model.
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SLIT2/ROBO1-miR-218-1-RET/PLAG1: a new disease pathway involved in Hirschsprung's disease.
Weibing Tang,Weibing Tang,Junwei Tang,Junwei Tang,Jun He,Zhigang Zhou,Zhigang Zhou,Yufeng Qin,Jingjing Qin,Jingjing Qin,Bo Li,Bo Li,Xiaoqun Xu,Xiaoqun Xu,Qiming Geng,Weiwei Jiang,Wei Wu,Xinru Wang,Yankai Xia +18 more
TL;DR: Altered miR‐218‐1 regulation of SLIT2, RET and PLAG1 might be involved in the pathogenesis of HSCR.
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The multi-targets integrated fingerprinting for screening anti-diabetic compounds from a Chinese medicine Jinqi Jiangtang Tablet.
Yan-xu Chang,Ai-hua Ge,Sineeporn Donnapee,Jin Li,Yang Bai,Jiao Liu,Jun He,Xi Yang,Li-jiao Song,Boli Zhang,Xiumei Gao +10 more
TL;DR: It is demonstrated that Jinqi Jiangtang Tablet can scavenge free radicals and inhibit α-glucosidase, aldose reductase, α-amylase and lipase, which may be the possible mechanism of action of Jinqijiang Tablet for the treatment of diabetes and associated complications.
Journal ArticleDOI
Simultaneous determination of four phenolic acids and seven alkaloids in rat plasma after oral administration of traditional Chinese medicinal preparation Jinqi Jiangtang Tablet by LC-ESI-MS/MS.
Yan-xu Chang,Ai-hua Ge,Xie-an Yu,Xiu-cheng Jiao,Jin Li,Jun He,Tian Ji,Wei Liu,John Teye Azietaku,Bo-li Zhang,Xiumei Gao +10 more
TL;DR: The developed method was applied to the pharmacokinetic study of 11 components after oral administration of traditional Chinese medicinal preparation Jinqi Jiangtang Tablet in rats and showed a good linearity over a wide concentration range.