J
Jun Luo
Researcher at Laboratory of Molecular Biology
Publications - 102
Citations - 2174
Jun Luo is an academic researcher from Laboratory of Molecular Biology. The author has contributed to research in topics: Lipid metabolism & Fatty acid synthesis. The author has an hindex of 24, co-authored 80 publications receiving 1560 citations. Previous affiliations of Jun Luo include Northwest A&F University & Southwest University of Science and Technology.
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Journal ArticleDOI
PPARγ Regulates Genes Involved in Triacylglycerol Synthesis and Secretion in Mammary Gland Epithelial Cells of Dairy Goats
Hengbo Shi,Jun Luo,Jiangjiang Zhu,Jun Li,Yuting Sun,Xianzi Lin,Liping Zhang,Dawei Yao,Huaiping Shi +8 more
TL;DR: Direct evidence is provided that PPARγ plays a crucial role in regulating the triacylglycerol synthesis and secretion in goat mammary cells and underscore the functional importance of PParγ in mammary gland tissue during lactation.
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Overexpression of SREBP1 (sterol regulatory element binding protein 1) promotes de novo fatty acid synthesis and triacylglycerol accumulation in goat mammary epithelial cells
TL;DR: Overall, the data provide strong support for a central role of SREBP1 in the regulation of milk fat synthesis in goat mammary cells.
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MiR-103 controls milk fat accumulation in goat (Capra hircus) mammary gland during lactation.
TL;DR: Functional analysis showed that over-expression of miR-103 in mammary gland epithelial cells increases transcription of genes associated with milk fat synthesis, resulting in an up-regulation of fat droplet formation, triglyceride accumulation, and the proportion of unsaturated fatty acids.
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MiR-27a suppresses triglyceride accumulation and affects gene mRNA expression associated with fat metabolism in dairy goat mammary gland epithelial cells.
TL;DR: This study provides the first experimental evidence that miR-27a regulates triglyceride synthesis in goat mammary gland epithelial cells and improves the understanding about the importance of miRNAs in milk fat synthesis.
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Acyl-CoA synthetase short-chain family member 2 (ACSS2) is regulated by SREBP-1 and plays a role in fatty acid synthesis in caprine mammary epithelial cells.
TL;DR: A novel pathway that SREBP‐1 may regulate fatty acid and TAG synthesis by regulating the expression of ACSS2 is revealed.