J
Junji Kurashige
Researcher at Kyushu University
Publications - 23
Citations - 1838
Junji Kurashige is an academic researcher from Kyushu University. The author has contributed to research in topics: Cancer & Metastasis. The author has an hindex of 15, co-authored 23 publications receiving 1500 citations.
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Journal ArticleDOI
Exosomal microRNA in serum is a novel biomarker of recurrence in human colorectal cancer
Tae Matsumura,K. Sugimachi,Hisae Iinuma,Yukiko Takahashi,Junji Kurashige,Genta Sawada,Masami Ueda,R Uchi,Hiroki Ueo,Yuki Takano,Yoshiaki Shinden,Hidetoshi Eguchi,Hiroyuki Yamamoto,Yuichiro Doki,Masaki Mori,Takahiro Ochiya,Koshi Mimori +16 more
TL;DR: Abundant expression of exosomal miR-19a in serum was identified as a prognostic biomarker for recurrence in CRC patients and showed poorer prognoses than the low expression group.
Journal ArticleDOI
Amplification of PVT-1 is involved in poor prognosis via apoptosis inhibition in colorectal cancers
Yusuke Takahashi,Genta Sawada,Junji Kurashige,Ryutaro Uchi,Tae Matsumura,Hiroki Ueo,Yuki Takano,Hidetoshi Eguchi,Tomoya Sudo,Keishi Sugimachi,Hirofumi Yamamoto,Yuichiro Doki,Masaki Mori,Koshi Mimori +13 more
TL;DR: PVT-1, which maps to 8q24, generates antiapoptotic activity in CRC, and abnormal expression of PVT-1 was a prognostic indicator for CRC patients, according to univariate and multivariate analysis.
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Clinical significance of the expression of long non-coding RNA HOTAIR in primary hepatocellular carcinoma
Masahisa Ishibashi,Ryunosuke Kogo,Kohei Shibata,Genta Sawada,Yusuke Takahashi,Junji Kurashige,Sayuri Akiyoshi,Shin Sasaki,Takeshi Iwaya,Tomoya Sudo,Keishi Sugimachi,Koshi Mimori,Go Wakabayashi,Masaki Mori +13 more
TL;DR: This study demonstrates that HOTAIR expression is associated with HCC progression, and introduction of human HOTA IR into liver cancer cells revealed that HotaIR promoted more rapid proliferation compared to control cells.
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Assessment of Sarcopenia as a Predictor of Poor Outcomes After Esophagectomy in Elderly Patients With Esophageal Cancer
Yuichiro Nakashima,Hiroshi Saeki,Ryota Nakanishi,Masahiko Sugiyama,Junji Kurashige,Eiji Oki,Yoshihiko Maehara +6 more
TL;DR: Sarcopenia and worse surgical outcomes were significantly associated patients with in esophageal cancer aged 65 years and older but not in those younger than 65 years.
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Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution.
Ryutaro Uchi,Yusuke Takahashi,Yusuke Takahashi,Atsushi Niida,Teppei Shimamura,Hidenari Hirata,Keishi Sugimachi,Genta Sawada,Genta Sawada,Takeshi Iwaya,Junji Kurashige,Yoshiaki Shinden,Tomohiro Iguchi,Hidetoshi Eguchi,Kenichi Chiba,Yuichi Shiraishi,Genta Nagae,Kenichi Yoshida,Yasunobu Nagata,Hiroshi Haeno,Hirofumi Yamamoto,Hideshi Ishii,Yuichiro Doki,Hisae Iinuma,Shin Sasaki,Satoshi Nagayama,Kazutaka Yamada,Shinichi Yachida,Mamoru Kato,Tatsuhiro Shibata,Eiji Oki,Hiroshi Saeki,Ken Shirabe,Yoshinao Oda,Yoshihiko Maehara,Shizuo Komune,Masaki Mori,Yutaka Suzuki,Ken Yamamoto,Hiroyuki Aburatani,Seishi Ogawa,Satoru Miyano,Koshi Mimori +42 more
TL;DR: A new model of colorectal cancer evolution is proposed, which is useful for understanding and confronting this heterogeneous disease and suggests extensive intratumor heterogeneity could be generated by neutral evolution.