H
Hisae Iinuma
Researcher at Teikyo University
Publications - 97
Citations - 4174
Hisae Iinuma is an academic researcher from Teikyo University. The author has contributed to research in topics: Cancer & Colorectal cancer. The author has an hindex of 32, co-authored 97 publications receiving 3540 citations.
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Journal ArticleDOI
Exosomal microRNA in serum is a novel biomarker of recurrence in human colorectal cancer
Tae Matsumura,K. Sugimachi,Hisae Iinuma,Yukiko Takahashi,Junji Kurashige,Genta Sawada,Masami Ueda,R Uchi,Hiroki Ueo,Yuki Takano,Yoshiaki Shinden,Hidetoshi Eguchi,Hiroyuki Yamamoto,Yuichiro Doki,Masaki Mori,Takahiro Ochiya,Koshi Mimori +16 more
TL;DR: Abundant expression of exosomal miR-19a in serum was identified as a prognostic biomarker for recurrence in CRC patients and showed poorer prognoses than the low expression group.
Journal ArticleDOI
Clinical Significance of Circulating Tumor Cells, Including Cancer Stem-Like Cells, in Peripheral Blood for Recurrence and Prognosis in Patients With Dukes' Stage B and C Colorectal Cancer
Hisae Iinuma,Toshiaki Watanabe,Koshi Mimori,Miki Adachi,Naoko Hayashi,Junko Tamura,Keiji Matsuda,Ryoji Fukushima,Kota Okinaga,Mitsuru Sasako,Masaki Mori +10 more
TL;DR: In patients with Dukes' stage B and C CRC who require adjuvant chemotherapy, detection of CEA/CK/CD133 mRNA in PB is a useful tool for determining which patients are at high risk for recurrence and poor prognosis.
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Clinicopathological and prognostic value of microRNA-21 and microRNA-155 in colorectal cancer.
TL;DR: Increases inmiR-21 and miR-155 expression levels in CRC tissue were independent prognostic factors for OS and DFS and may represent effective biomarkers for the prediction of a poor prognosis.
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Plastin3 is a novel marker for circulating tumor cells undergoing the epithelial-mesenchymal transition and is associated with colorectal cancer prognosis
Takehiko Yokobori,Hisae Iinuma,Teppei Shimamura,Seiya Imoto,Keishi Sugimachi,Hideshi Ishii,Masaaki Iwatsuki,Daisuke Ota,Masahisa Ohkuma,Takeshi Iwaya,Naohiro Nishida,Ryunosuke Kogo,Tomoya Sudo,Fumiaki Tanaka,Kohei Shibata,Hiroyuki Toh,Tetsuya Sato,Graham F. Barnard,Takeo Fukagawa,Seiichiro Yamamoto,Hayao Nakanishi,Shin Sasaki,Satoru Miyano,Toshiaki Watanabe,Hiroyuki Kuwano,Koshi Mimori,Klaus Pantel,Masaki Mori +27 more
TL;DR: PLS3-positive CTC was independently associated with prognosis in the training set and the validation set, and it possesses significant prognostic value.
Journal ArticleDOI
Intracellular targeting therapy of cisplatin-encapsulated transferrin-polyethylene glycol liposome on peritoneal dissemination of gastric cancer.
Hisae Iinuma,Kazuo Maruyama,Kota Okinaga,Katsunori Sasaki,Toshiyuki Sekine,Osamu Ishida,Naoko Ogiwara,Kohei Johkura,Yutaka Yonemura +8 more
TL;DR: It is suggested that cisplatin‐encapsulated Tf‐PEG liposomes may be useful as a new intracellular targeting carrier for treatment of gastric cancer with peritoneal dissemination.