S
Shin Sasaki
Researcher at University of Tokyo
Publications - 70
Citations - 3581
Shin Sasaki is an academic researcher from University of Tokyo. The author has contributed to research in topics: Cancer & Colorectal cancer. The author has an hindex of 21, co-authored 64 publications receiving 3309 citations. Previous affiliations of Shin Sasaki include Kyushu University.
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Journal ArticleDOI
The medaka draft genome and insights into vertebrate genome evolution
Masahiro Kasahara,Kiyoshi Naruse,Shin Sasaki,Yoichiro Nakatani,Wei Qu,Budrul Ahsan,Tomoyuki Yamada,Yukinobu Nagayasu,Koichiro Doi,Yasuhiro Kasai,Tomoko Jindo,Daisuke Kobayashi,Atsuko Shimada,Atsushi Toyoda,Yoko Kuroki,Asao Fujiyama,Takashi Sasaki,Atsushi Shimizu,Shuichi Asakawa,Nobuyoshi Shimizu,Shin-ichi Hashimoto,Jun Yang,Yongjun Lee,Kouji Matsushima,Sumio Sugano,Mitsuru Sakaizumi,Takanori Narita,Takanori Narita,Kazuko Ohishi,Shinobu Haga,Fumiko Ohta,Hisayo Nomoto,Keiko Nogata,Tomomi Morishita,Tomoko Endo,Tadasu Shin-I,Hiroyuki Takeda,Shinichi Morishita,Yuji Kohara +38 more
TL;DR: A high-quality draft genome sequence of a small egg-laying freshwater teleost, medaka, revealed that eight major interchromosomal rearrangements took place in a remarkably short period of ∼50 Myr after the whole-genome duplication event in the teleost ancestor and afterwards, intriguingly, the medaka genome preserved its ancestral karyotype for more than 300Myr.
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The genome sequence of silkworm, Bombyx mori
Kazuei Mita,Masahiro Kasahara,Shin Sasaki,Yukinobu Nagayasu,Tomoyuki Yamada,Hiroyuki Kanamori,Nobukazu Namiki,Masanari Kitagawa,Hidetoshi Yamashita,Yuji Yasukochi,Keiko Kadono-Okuda,Kimiko Yamamoto,Masahiro Ajimura,Gopalapillai Ravikumar,Michihiko Shimomura,Yoshiaki Nagamura,Tadasu Shin-I,Hiroaki Abe,Toru Shimada,Shinichi Morishita,Takuji Sasaki +20 more
TL;DR: Analysis of the WGS data revealed that the silkworm genome contains many repetitive sequences with an average length of <500 bp, which suggests that silkworm may have an active mechanism that promotes removal of transposons from the genome.
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Clinical significance of the expression of long non-coding RNA HOTAIR in primary hepatocellular carcinoma
Masahisa Ishibashi,Ryunosuke Kogo,Kohei Shibata,Genta Sawada,Yusuke Takahashi,Junji Kurashige,Sayuri Akiyoshi,Shin Sasaki,Takeshi Iwaya,Tomoya Sudo,Keishi Sugimachi,Koshi Mimori,Go Wakabayashi,Masaki Mori +13 more
TL;DR: This study demonstrates that HOTAIR expression is associated with HCC progression, and introduction of human HOTA IR into liver cancer cells revealed that HotaIR promoted more rapid proliferation compared to control cells.
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Plastin3 is a novel marker for circulating tumor cells undergoing the epithelial-mesenchymal transition and is associated with colorectal cancer prognosis
Takehiko Yokobori,Hisae Iinuma,Teppei Shimamura,Seiya Imoto,Keishi Sugimachi,Hideshi Ishii,Masaaki Iwatsuki,Daisuke Ota,Masahisa Ohkuma,Takeshi Iwaya,Naohiro Nishida,Ryunosuke Kogo,Tomoya Sudo,Fumiaki Tanaka,Kohei Shibata,Hiroyuki Toh,Tetsuya Sato,Graham F. Barnard,Takeo Fukagawa,Seiichiro Yamamoto,Hayao Nakanishi,Shin Sasaki,Satoru Miyano,Toshiaki Watanabe,Hiroyuki Kuwano,Koshi Mimori,Klaus Pantel,Masaki Mori +27 more
TL;DR: PLS3-positive CTC was independently associated with prognosis in the training set and the validation set, and it possesses significant prognostic value.
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Aberrant expression of lysophosphatidic acid (LPA) receptors in human colorectal cancer.
Dai Shida,Toshiaki Watanabe,Junken Aoki,Kotaro Hama,Joji Kitayama,Hirofumi Sonoda,Yasuhiro Kishi,Hironori Yamaguchi,Shin Sasaki,Akihiro Sako,Tsuyoshi Konishi,Hiroyuki Arai,Hirokazu Nagawa +12 more
TL;DR: It is suggested that alteration of LPA receptor expression might be an important event in the development of colorectal cancer, and therefore, LPA and its receptors could be a chemopreventive target against coloreCTal cancer.