Y
Yuki Takano
Researcher at Kyushu University
Publications - 27
Citations - 1519
Yuki Takano is an academic researcher from Kyushu University. The author has contributed to research in topics: Cancer & Metastasis. The author has an hindex of 15, co-authored 27 publications receiving 1287 citations.
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Journal ArticleDOI
Exosomal microRNA in serum is a novel biomarker of recurrence in human colorectal cancer
Tae Matsumura,K. Sugimachi,Hisae Iinuma,Yukiko Takahashi,Junji Kurashige,Genta Sawada,Masami Ueda,R Uchi,Hiroki Ueo,Yuki Takano,Yoshiaki Shinden,Hidetoshi Eguchi,Hiroyuki Yamamoto,Yuichiro Doki,Masaki Mori,Takahiro Ochiya,Koshi Mimori +16 more
TL;DR: Abundant expression of exosomal miR-19a in serum was identified as a prognostic biomarker for recurrence in CRC patients and showed poorer prognoses than the low expression group.
Journal ArticleDOI
Amplification of PVT-1 is involved in poor prognosis via apoptosis inhibition in colorectal cancers
Yusuke Takahashi,Genta Sawada,Junji Kurashige,Ryutaro Uchi,Tae Matsumura,Hiroki Ueo,Yuki Takano,Hidetoshi Eguchi,Tomoya Sudo,Keishi Sugimachi,Hirofumi Yamamoto,Yuichiro Doki,Masaki Mori,Koshi Mimori +13 more
TL;DR: PVT-1, which maps to 8q24, generates antiapoptotic activity in CRC, and abnormal expression of PVT-1 was a prognostic indicator for CRC patients, according to univariate and multivariate analysis.
Journal Article
A Long Noncoding RNA, lncRNA-ATB, Is Involved in the Progression and Prognosis of Colorectal Cancer
Tomohiro Iguchi,Ryutaro Uchi,Sho Nambara,Tomoko Saito,Hisateru Komatsu,Hidenari Hirata,Masami Ueda,Shotaro Sakimura,Yuki Takano,Jyunji Kurashige,Yoshiaki Shinden,Hidetoshi Eguchi,Keishi Sugimachi,Yoshihiko Maehara,Koshi Mimori +14 more
TL;DR: High lncRNA-ATB expression was significantly associated with greater tumor size, depth of tumor invasion, lymphatic invasion, vascular invasion, and lymph node metastasis and may be a novel indicator of poor prognosis in patients with CRC.
Journal ArticleDOI
Circulating exosomal microRNA-203 is associated with metastasis possibly via inducing tumor-associated macrophages in colorectal cancer.
Yuki Takano,Takaaki Masuda,Hisae Iinuma,Rui Yamaguchi,Kuniaki Sato,Taro Tobo,Hidenari Hirata,Yosuke Kuroda,Sho Nambara,Naoki Hayashi,Tomohiro Iguchi,Shuhei Ito,Hidetoshi Eguchi,Takahiro Ochiya,Katsuhiko Yanaga,Satoru Miyano,Koshi Mimori +16 more
TL;DR: Serum exosomal miR-203 expression is a novel biomarker for predicting metastasis, possibly via promoting the differentiation of monocytes to M2-TAMs in CRC patients, and the concept of site-dependent functions for mi R-203 in tumor progression is proposed.
Journal ArticleDOI
A Long Non-coding RNA Activated by Transforming Growth Factor-β is an Independent Prognostic Marker of Gastric Cancer.
Tomoko Saito,Junji Kurashige,Sho Nambara,Hisateru Komatsu,Hidenari Hirata,Masami Ueda,Shotaro Sakimura,Ryutaro Uchi,Yuki Takano,Yoshiaki Shinden,Tomohiro Iguchi,Hidetoshi Eguchi,Shogo Ehata,Kazunari Murakami,Keishi Sugimachi,Koshi Mimori +15 more
TL;DR: LncRNA-ATB plays an important role in EMT to promote invasion and metastasis through the TGF-β/miR-200s/ZEB axis, resulting in a poor prognosis in GC patients.