J
Junyun He
Researcher at University of Maryland, Baltimore
Publications - 40
Citations - 1450
Junyun He is an academic researcher from University of Maryland, Baltimore. The author has contributed to research in topics: Microglia & Neuroinflammation. The author has an hindex of 15, co-authored 34 publications receiving 1006 citations. Previous affiliations of Junyun He include Pennington Biomedical Research Center & Arizona State University.
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Journal ArticleDOI
3D Printed Anatomical Nerve Regeneration Pathways.
Blake N. Johnson,Blake N. Johnson,Karen Z. Lancaster,Gehua Zhen,Junyun He,Maneesh K. Gupta,Yong Lin Kong,Esteban A. Engel,Kellin Krick,Alex Ju,Fanben Meng,Lynn W. Enquist,Xiaofeng Jia,Michael C. McAlpine +13 more
TL;DR: An imaging-coupled 3D printing methodology for the design, optimization, and fabrication of a customized nerve repair technology for complex injuries is presented.
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Geminiviral vectors based on bean yellow dwarf virus for production of vaccine antigens and monoclonal antibodies in plants
TL;DR: Several vaccine antigens, including Norwalk virus capsid protein and hepatitis B core antigen, were expressed using the BeYDV vector at levels up to 1mg per g of leaf mass, and the protective mAb 6D8 against Ebola virus was produced.
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Sleep restriction impairs blood-brain barrier function.
TL;DR: It is proposed that changes of the BBB contribute to many pathophysiological processes in the brain of subjects with chronic sleep restriction (CSR), and that CSR compromises microvascular function.
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Robust production of virus‐like particles and monoclonal antibodies with geminiviral replicon vectors in lettuce
TL;DR: This study explored the use of lettuce, which grows quickly yet produces low levels of secondary metabolites and viral vector-based transient expression systems to develop a robust PMP production platform and establishes a new production platform for biological pharmaceutical agents that are effective, safe, low cost, and amenable to large-scale manufacturing.
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Delayed microglial depletion after spinal cord injury reduces chronic inflammation and neurodegeneration in the brain and improves neurological recovery in male mice.
Yun Li,Rodney M. Ritzel,Niaz Khan,Tuoxin Cao,Junyun He,Zhuofan Lei,Jessica J. Matyas,Boris Sabirzhanov,Simon Liu,Hui Li,Bogdan A. Stoica,David J. Loane,Alan I. Faden,Junfang Wu +13 more
TL;DR: Findings indicate that pharmacological microglia-deletion reduces neuroinflammation in the injured spinal cord and brain, improving recovery of cognition, depressive-like behavior, and motor function.