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Xiaofeng Jia
Researcher at University of Maryland, Baltimore
Publications - 156
Citations - 5231
Xiaofeng Jia is an academic researcher from University of Maryland, Baltimore. The author has contributed to research in topics: Hypothermia & Stem cell. The author has an hindex of 31, co-authored 130 publications receiving 3886 citations. Previous affiliations of Xiaofeng Jia include Johns Hopkins University & Johns Hopkins Bayview Medical Center.
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Journal ArticleDOI
Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis
Gehua Zhen,Chunyi Wen,Chunyi Wen,Xiaofeng Jia,Yu Li,Janet L. Crane,Simon C. Mears,Frederic B. Askin,Frank J. Frassica,Weizhong Chang,Jie Yao,John A. Carrino,Andrew J. Cosgarea,Dmitri Artemov,Qianming Chen,Zhihe Zhao,Xuedong Zhou,Lee H. Riley,Paul D. Sponseller,Mei Wan,William W. Lu,William W. Lu,Xu Cao +22 more
TL;DR: It is shown that transforming growth factor β1 is activated in subchondral bone in response to altered mechanical loading in an anterior cruciate ligament transection mouse model of osteoarthritis, and inhibition of this process could be a potential therapeutic approach to treating this disease.
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Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells
Lingling Xian,Xiangwei Wu,Xiangwei Wu,Lijuan Pang,Lijuan Pang,Michael Lou,Clifford J. Rosen,Tao Qiu,Janet L. Crane,Frank J. Frassica,Liming Zhang,Juan Pablo Rodríguez,Xiaofeng Jia,Shoshana Yakar,Shouhong Xuan,Argiris Efstratiadis,Mei Wan,Xu Cao +17 more
TL;DR: It is reported that IGF-1 released from the bone matrix during bone remodeling stimulates osteoblastic differentiation of recruited mesenchymal stem cells by activation of mammalian target of rapamycin (mTOR), thus maintaining proper bone microarchitecture and mass.
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Three-dimensional (3D) printed scaffold and material selection for bone repair
TL;DR: This review provides a brief overview of current progress in existing biomaterials and tissue engineering scaffolds prepared by 3D printing technologies, with an emphasis on the material selection, scaffold design optimization, and their preclinical and clinical applications in the repair of critical-sized bone defects.
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3D Printed Anatomical Nerve Regeneration Pathways.
Blake N. Johnson,Blake N. Johnson,Karen Z. Lancaster,Gehua Zhen,Junyun He,Maneesh K. Gupta,Yong Lin Kong,Esteban A. Engel,Kellin Krick,Alex Ju,Fanben Meng,Lynn W. Enquist,Xiaofeng Jia,Michael C. McAlpine +13 more
TL;DR: An imaging-coupled 3D printing methodology for the design, optimization, and fabrication of a customized nerve repair technology for complex injuries is presented.
Journal ArticleDOI
Engineering anatomically shaped vascularized bone grafts with hASCs and 3D‐printed PCL scaffolds
Joshua P. Temple,Daphne L. Hutton,Ben P. Hung,Pinar Yilgor Huri,Colin A. Cook,Renu Kondragunta,Xiaofeng Jia,Warren L. Grayson +7 more
TL;DR: The capabilities and potential of 3D printed scaffolds to be used for engineering autologous, anatomically shaped, vascularized bone grafts are illustrated.