J
Jürgen K. Mai
Researcher at University of Düsseldorf
Publications - 61
Citations - 3953
Jürgen K. Mai is an academic researcher from University of Düsseldorf. The author has contributed to research in topics: Epitope & Deep brain stimulation. The author has an hindex of 25, co-authored 60 publications receiving 3755 citations. Previous affiliations of Jürgen K. Mai include Sanford-Burnham Institute for Medical Research.
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Book
The human nervous system
George Paxinos,Jürgen K. Mai +1 more
TL;DR: This book describes the development of the central nervous system and some of the mechanisms leading to cell death and organ failure in animals and humans.
Journal ArticleDOI
Deep brain stimulation of the nucleus basalis of Meynert in Alzheimer's dementia.
Jens Kuhn,K. Hardenacke,Doris Lenartz,Theo O.J. Gruendler,Markus Ullsperger,C Bartsch,Jürgen K. Mai,Karl Zilles,Andreas Bauer,Andreas Matusch,R.-J. Schulz,Michaela Noreik,Christian Bührle,David Maintz,Christiane Woopen,P. Häussermann,Martin Hellmich,Joachim Klosterkötter,Jens Wiltfang,Mohammad Maarouf,H.-J. Freund,Volker Sturm +21 more
TL;DR: It is concluded that DBS of the NBM is both technically feasible and well tolerated and on the basis of stable or improved primary outcome parameters twelve months after surgery, four of the six patients were considered responders.
Journal ArticleDOI
Substance P in the human brain.
TL;DR: These studies demonstrated that substance P immunoreactivity was preserved in archival material permitting a detailed account of the localization of immunoreactive cell bodies, fibre networks and tracts in the human brain.
Journal ArticleDOI
Cognitive functions in a patient with Parkinson-dementia syndrome undergoing deep brain stimulation.
Hans-Joachim Freund,Jens Kuhn,Doris Lenartz,Jürgen K. Mai,Thomas Schnell,J. Klosterkoetter,Volker Sturm +6 more
TL;DR: A broad effect on cognition is consistent with ample experimental evidence revealing that the nucleus basalis of Meynert provides cholinergic innervation to the cortical mantle, complemented by glutaminergic and gamma-aminobutyric acid-transmitting projections from the basal forebrain.
Journal ArticleDOI
Dynamics of expression of apoptosis-regulatory proteins Bid, Bcl-2, Bcl-X, Bax and Bak during development of murine nervous system.
Maryla Krajewska,Jürgen K. Mai,Juan M. Zapata,Ken W.S. Ashwell,Ken W.S. Ashwell,Sharon L. Schendel,John C. Reed,Stan Krajewski +7 more
TL;DR: The p15 cleaved form of Bid was detectable in the brain specimens at fetal stages of development, consistent with caspase-mediated activation of this pro-apoptotic Bcl-2 family protein.