J
Jens Kuhn
Researcher at University of Cologne
Publications - 158
Citations - 6083
Jens Kuhn is an academic researcher from University of Cologne. The author has contributed to research in topics: Deep brain stimulation & Tourette syndrome. The author has an hindex of 37, co-authored 147 publications receiving 5006 citations. Previous affiliations of Jens Kuhn include National Institutes of Health.
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Journal ArticleDOI
Deep Brain Stimulation for Obsessive-Compulsive Disorder: A Meta-Analysis of Treatment Outcome and Predictors of Response
Pino Alonso,Daniel Cuadras,Loes Gabriëls,Damiaan Denys,Wayne K. Goodman,Ben D. Greenberg,Fiacro Jimenez-Ponce,Jens Kuhn,Doris Lenartz,Luc Mallet,Bart Nuttin,Eva Real,Cinto Segalàs,Rick Schuurman,Sophie Tezenas du Montcel,José M. Menchón +15 more
TL;DR: It is confirmed that DBS constitutes a valid alternative to lesional surgery for severe, therapy-refractory OCD patients and well-controlled, randomized studies with larger samples are needed to establish the optimal targeting and stimulation conditions.
Journal ArticleDOI
Unilateral deep brain stimulation of the nucleus accumbens in patients with treatment-resistant obsessive-compulsive disorder: Outcomes after one year.
W. Huff,Doris Lenartz,Michael Schormann,S. H. Lee,Jens Kuhn,Anastosious Koulousakis,Juergen Mai,Joerg Daumann,Mohammad Maarouf,Joachim Klosterkötter,Volker Sturm +10 more
TL;DR: DBS of the unilateral right nucleus accumbens showed encouraging results in patients with treatment-resistant OCD, and anxiety, global symptom severity and cognitive function showed no significant changes.
Journal ArticleDOI
Prepulse inhibition in psychiatric disorders – Apart from schizophrenia
TL;DR: PPI is deficient in obsessive compulsive disorder (OCD) and Gilles de la Tourette's syndrome (GTS), and in bipolar disorder dysfunctional PPI seems to be rather state dependent.
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Remission of alcohol dependency following deep brain stimulation of the nucleus accumbens: valuable therapeutic implications?
Jens Kuhn,Doris Lenartz,Wolfgang Huff,S. H. Lee,Athanasios Koulousakis,J. Klosterkoetter,Volker Sturm +6 more
TL;DR: A 54-year-old patient with a severe anxiety disorder and secondary depressive disorder in whom bilateral deep brain stimulation of the nucleus accumbens was carried out observes a remarkable although not primarily intended alleviation of the patient’s comorbid alcohol dependency.
Journal ArticleDOI
Tourette syndrome deep brain stimulation: A review and updated recommendations
Lauren E. Schrock,Jonathan W. Mink,Douglas W. Woods,Mauro Porta,Dominico Servello,Veerle Visser-Vandewalle,Peter A. Silburn,Thomas Foltynie,Harrison C. Walker,Joohi Shahed-Jimenez,Rodolfo Savica,Bryan T. Klassen,Andre G. Machado,Kelly D. Foote,Jian-Guo Zhang,Wei Hu,Linda Ackermans,Yasin Temel,Zoltan Mari,Barbara Changizi,Andres M. Lozano,Man Auyeung,Takanobu Kaido,Yves Agid,Marie L. Welter,Suketu M. Khandhar,Alon Y. Mogilner,Michael H. Pourfar,Benjamin L. Walter,Jorge L. Juncos,Robert E. Gross,Jens Kuhn,James F. Leckman,Joseph A. Neimat,Michael S. Okun +34 more
TL;DR: Tourette syndrome DBS, though still evolving, is a promising approach for a subset of medication refractory and severely affected patients and should be offered to patients only by experienced DBS centers after evaluation by a multidisciplinary team.