K
K A Fitzgerald
Researcher at Harvard University
Publications - 44
Citations - 5809
K A Fitzgerald is an academic researcher from Harvard University. The author has contributed to research in topics: Antigen & T cell. The author has an hindex of 25, co-authored 40 publications receiving 5744 citations. Previous affiliations of K A Fitzgerald include University of Missouri–Kansas City & University of Missouri.
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Journal ArticleDOI
An alternative pathway of T-cell activation: A functional role for the 50 kd T11 sheep erythrocyte receptor protein
Stefan Meuer,Rebecca E. Hussey,Marina Fabbi,David A. Fox,Oreste Acuto,K A Fitzgerald,James C. Hodgdon,Jeffrey P. Protentis,Stuart F. Schlossman,Ellis L. Reinherz +9 more
TL;DR: Given that T11 is the earliest T-lineage surface glycoprotein to appear in thymic ontogeny and is thus expressed before T3-Ti, the former may be involved in clonal expansion and/or differentiation during early development.
Journal ArticleDOI
Clonotypic structures involved in antigen-specific human T cell function. Relationship to the T3 molecular complex.
Stefan Meuer,K A Fitzgerald,Rebecca E. Hussey,James C. Hodgdon,Stuart F. Schlossman,Ellis L. Reinherz +5 more
TL;DR: The development of monoclonal antibodies to such polymorphic T cell surface structures should provide important probes to further define the surface receptor for antigen.
Journal ArticleDOI
Antigen recognition by human T lymphocytes is linked to surface expression of the T3 molecular complex.
Ellis L. Reinherz,Stefan Meuer,K A Fitzgerald,Rebecca E. Hussey,Herbert Levine,Stuart F. Schlossman +5 more
TL;DR: Evidence is provided for a direct linkage between antigen recognition by T lymphocytes and surface expression of the T3 molecular complex, which inhibits cytotoxic T lymphocyte effector function by T4 and T8 clones as well as antigen-specific T cell recognition.
Journal ArticleDOI
Evidence for the T3-associated 90K heterodimer as the T-cell antigen receptor
Stefan Meuer,Oreste Acuto,Rebecca E. Hussey,James C. Hodgdon,K A Fitzgerald,Stuart F. Schlossman,Ellis L. Reinherz +6 more
TL;DR: It is suggested that each T lymphocyte, regardless of subset derivation or specificity, uses an analogous Ti heterodimer for antigen specific function.
Journal Article
Heterogeneity of human T4+ inducer T cells defined by a monoclonal antibody that delineates two functional subpopulations.
Ellis L. Reinherz,Chikao Morimoto,K A Fitzgerald,Rebecca E. Hussey,John F. Daley,Stuart F. Schlossman +5 more
TL;DR: It is concluded that the subpopulation of T4+ inducer cells responsible for maximal helper activity in T-B interactions is restricted to a minor subpopulations of T3+ T lymphocytes delineated by anti-TQ1.