K
K. K. Bucholz
Researcher at Washington University in St. Louis
Publications - 40
Citations - 5960
K. K. Bucholz is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Alcohol dependence & Poison control. The author has an hindex of 30, co-authored 40 publications receiving 5675 citations.
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Journal ArticleDOI
A new, semi-structured psychiatric interview for use in genetic linkage studies: a report on the reliability of the SSAGA.
K. K. Bucholz,R. Cadoret,C. R. Cloninger,S. H. Dinwiddie,Victor Hesselbrock,John I. Nurnberger,T. Reich,I. Schmidt,Marc A. Schuckit +8 more
TL;DR: Although SSAGA was designed to provide for broad phenotyping of alcoholism, review of its new features suggests its suitability for a variety of family studies, not just those focusing on substance abuse.
Journal ArticleDOI
Genetic and environmental contributions to alcohol dependence risk in a national twin sample: consistency of findings in women and men
Andrew C. Heath,K. K. Bucholz,Pamela A. F. Madden,Stephen H. Dinwiddie,Wendy S. Slutske,Laura J. Bierut,Dixie J. Statham,Michael P. Dunne,John Whitfield,Nicholas G. Martin +9 more
TL;DR: In a follow-up interview with twins from an Australian twin panel first surveyed in 1980-82 (N=5889 respondents), data were analysed using logistic regression models and no significant gender difference in the genetic variance in AD was found as mentioned in this paper.
Journal ArticleDOI
Early sexual abuse and lifetime psychopathology: a co-twin-control study.
Stephen H. Dinwiddie,Andrew C. Heath,Michael P. Dunne,K. K. Bucholz,Pamela A. F. Madden,Wendy S. Slutske,Laura J. Bierut,D. B. Statham,Nicholas G. Martin +8 more
TL;DR: The association between CSA and psychopathology arises at least in part through the influence of shared familial factors on both risk of victimization and risk of psychopathology.
Journal ArticleDOI
Genetic differences in alcohol sensitivity and the inheritance of alcoholism risk.
Andrew C. Heath,P. A. F. Madden,K. K. Bucholz,Stephen H. Dinwiddie,Wendy S. Slutske,Laura J. Bierut,John W. Rohrbaugh,Dixie J. Statham,Michael P. Dunne,John Whitfield,Nicholas G. Martin +10 more
TL;DR: Men (but not women) at increased genetic risk of alcohol dependence (assessed by MZ co-twin's history ofalcohol dependence) exhibited reduced alcohol sensitivity, and associations with parental alcoholism were inconsistent.
Journal ArticleDOI
Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence
Jen-Chyong Wang,Richard A. Grucza,Carlos Cruchaga,Anthony L. Hinrichs,Sarah Bertelsen,John P. Budde,Louis Fox,E Goldstein,Oliver Reyes,Nancy L. Saccone,Scott F. Saccone,Xiaoling Xuei,K. K. Bucholz,Samuel Kuperman,Jr Ji Nurnberger,John P. Rice,Marc A. Schuckit,Jay A. Tischfield,Victor Hesselbrock,Bernice Porjesz,Howard J. Edenberg,Laura J. Bierut,Alison Goate +22 more
TL;DR: It is observed that a different group of polymorphisms, spanning CHRNA5-CHRNA3, demonstrate association with alcohol dependence defined by Diagnostic and Statistical Manual of Mental Disorders, 4th edn (DSM-IV) criteria.