P
P. A. F. Madden
Researcher at Washington University in St. Louis
Publications - 35
Citations - 2392
P. A. F. Madden is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Alcohol dependence & Population. The author has an hindex of 23, co-authored 34 publications receiving 1980 citations.
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Journal ArticleDOI
Meta-analysis of genome-wide association studies of anxiety disorders.
Takeshi Otowa,Takeshi Otowa,Karin Hek,Minyoung Lee,Enda M. Byrne,Enda M. Byrne,Saira Saeed Mirza,Michel G. Nivard,Timothy B. Bigdeli,Steven H. Aggen,Daniel E. Adkins,Aaron R. Wolen,Ayman H. Fanous,Ayman H. Fanous,Matthew C. Keller,Enrique Castelao,Zoltán Kutalik,Zoltán Kutalik,Zoltán Kutalik,S. V. der Auwera,Georg Homuth,Matthias Nauck,Alexander Teumer,Yuri Milaneschi,Yuri Milaneschi,Jouke-Jan Hottenga,Jouke-Jan Hottenga,Nese Direk,Albert Hofman,André G. Uitterlinden,Cornelis L. Mulder,Anjali K. Henders,Anjali K. Henders,Sarah E. Medland,Scott D. Gordon,A. C. Heath,P. A. F. Madden,Michele L. Pergadia,Michele L. Pergadia,P. J. van der Most,Ilja M. Nolte,F. V. A. van Oort,Catharina A. Hartman,Albertine J. Oldehinkel,Martin Preisig,Hans-Jörgen Grabe,Christel M. Middeldorp,Christel M. Middeldorp,Brenda W.J.H. Penninx,Dorret I. Boomsma,Nicholas G. Martin,Grant W. Montgomery,Brion S. Maher,E J C G van den Oord,Naomi R. Wray,Naomi R. Wray,Henning Tiemeier,Henning Tiemeier,John M. Hettema +58 more
TL;DR: To identify genetic variants contributing to genetic susceptibility shared across interview-generated DSM-based ADs, two phenotypic approaches were applied: (1) comparisons between categorical AD cases and supernormal controls, and (2) quantitative Phenotypic factor scores derived from a multivariate analysis combining information across the clinical phenotypes.
Journal ArticleDOI
Genetic differences in alcohol sensitivity and the inheritance of alcoholism risk.
Andrew C. Heath,P. A. F. Madden,K. K. Bucholz,Stephen H. Dinwiddie,Wendy S. Slutske,Laura J. Bierut,John W. Rohrbaugh,Dixie J. Statham,Michael P. Dunne,John Whitfield,Nicholas G. Martin +10 more
TL;DR: Men (but not women) at increased genetic risk of alcohol dependence (assessed by MZ co-twin's history ofalcohol dependence) exhibited reduced alcohol sensitivity, and associations with parental alcoholism were inconsistent.
Journal ArticleDOI
A direct test of the diathesis-stress model for depression.
Lucía Colodro-Conde,Lucía Colodro-Conde,Baptiste Couvy-Duchesne,Baptiste Couvy-Duchesne,Gu Zhu,William L. Coventry,Enda M. Byrne,Scott D. Gordon,Margaret J. Wright,Grant W. Montgomery,P. A. F. Madden,Stephan Ripke,Stephan Ripke,Stephan Ripke,Lindon J. Eaves,A. C. Heath,Naomi R. Wray,Sarah E. Medland,Nicholas G. Martin +18 more
TL;DR: An extra risk for individuals with combined vulnerability and high number of reported personal life events beyond what would be expected from the additive contributions of these factors to the liability for depression, supporting the multiplicative diathesis–stress model for this disease.
Journal ArticleDOI
Erratum: Meta-analysis of genome-wide association studies of anxiety disorders (vol 21, pg 1391, 2016)
Takeshi Otowa,Karin Hek,Minyoung Lee,Enda M. Byrne,Saira Saeed Mirza,Michel G. Nivard,Timothy B. Bigdeli,Steven H. Aggen,Daniel E. Adkins,Aaron R. Wolen,Ayman H. Fanous,Matthew C. Keller,Enrique Castelao,Z. Kutalik,S. V. der Auwera,Georg Homuth,Matthias Nauck,A. Teumer,Y. Milaneschi,J-J Hottenga,Nese Direk,A. Hofman,A.G. Uitterlinden,Cornelis L. Mulder,Anjali K. Henders,S. E. Medland,Scott D. Gordon,A. C. Heath,P. A. F. Madden,M. L. Pergadia,P. J. van der Most,Ilja M. Nolte,F. V. A. van Oort,C.A. Hartman,Albertine J. Oldehinkel,Martin Preisig,Hans-Jörgen Grabe,Christel M. Middeldorp,B.W.J.H. Penninx,D.I. Boomsma,Nicholas G. Martin,Grant W. Montgomery,Brion S. Maher,E. J. C. G. van den Oord,N. R. Wray,Henning Tiemeier,John M. Hettema +46 more
TL;DR: The fifteenth author's name was presented incorrectly and the author’s name should have appeared as S Van der Auwera and the publisher regrets the error.
Journal ArticleDOI
Social phobia in a population-based female adolescent twin sample: co-morbidity and associated suicide-related symptoms.
Elliot C. Nelson,Julia D. Grant,K. K. Bucholz,Anne L. Glowinski,P. A. F. Madden,Wendy Reich,Andrew C. Heath +6 more
TL;DR: SP with co-morbid MDD predicts a substantially elevated risk of ALD and suicide-related symptoms, stressing the need for early SP detection.