K
Kaisa Huhtinen
Researcher at University of Turku
Publications - 71
Citations - 1987
Kaisa Huhtinen is an academic researcher from University of Turku. The author has contributed to research in topics: Ovarian cancer & Cancer. The author has an hindex of 20, co-authored 50 publications receiving 1570 citations. Previous affiliations of Kaisa Huhtinen include Solvay & Turku University Hospital.
Papers
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Journal ArticleDOI
Serum HE4 concentration differentiates malignant ovarian tumours from ovarian endometriotic cysts
Kaisa Huhtinen,Pia Suvitie,Jukka Hiissa,J Junnila,Jutta Huvila,Harry Kujari,Marjaleena Setälä,Päivi Härkki,Jyrki Jalkanen,J. Fraser,Juha Mäkinen,Annika Auranen,Matti Poutanen,Antti Perheentupa,Antti Perheentupa +14 more
TL;DR: Taking together, measuring both HE4 and CA125 serum concentrations increases the accuracy of ovarian cancer diagnosis and provides valuable information to discriminate ovarian tumours from ovarian endometriotic cysts.
Journal ArticleDOI
The androgen and progesterone receptors regulate distinct gene networks and cellular functions in decidualizing endometrium.
Brianna Cloke,Kaisa Huhtinen,Luca Fusi,Takeshi Kajihara,Takeshi Kajihara,Maria Yliheikkilä,Ka Kei Ho,Gijs Teklenburg,Stuart Lavery,Marius C. Jones,Geoffrey Trew,Geoffrey Trew,J. Julie Kim,Eric Lam,Judith E. Cartwright,Matti Poutanen,Jan J. Brosens +16 more
TL;DR: The nonredundant function of the AR in decidualizing HESCs, centered on cytoskeletal organization and cell cycle regulation, implies an important role for androgens in modulating fetal-maternal interactions.
Journal ArticleDOI
Endometrial and Endometriotic Concentrations of Estrone and Estradiol Are Determined by Local Metabolism Rather than Circulating Levels
Kaisa Huhtinen,Reena Desai,Mia Ståhle,Anu Salminen,David J. Handelsman,Antti Perheentupa,Antti Perheentupa,Matti Poutanen,Matti Poutanen +8 more
TL;DR: Endometrial or endometriotic tissue E2 concentrations are actively regulated by local estrogen metabolism in the tissue, and the inhibition of local E2 synthesis is a valid, novel approach to reduce local E1-dependent growth of endometiotic tissue.
Journal Article
Pathogenesis of endometriosis
TL;DR: Of women of reproductive age, 6 to 10% are estimated to be affected by endometriosis, which causes severe menstrual pain, chronic pelvic pain and infertility for the patients.
Journal ArticleDOI
Fast and sensitive liquid chromatography–mass spectrometry assay for seven androgenic and progestagenic steroids in human serum
TL;DR: A fast and sensitive LC-MS/MS method for the quantitative analysis of seven steroid hormones in 150 μl of human serum was developed and validated and applied for the serum steroid profiling of endometriosis patients.