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Karena Pryce
Researcher at University of Queensland
Publications - 9
Citations - 2139
Karena Pryce is an academic researcher from University of Queensland. The author has contributed to research in topics: Ankylosing spondylitis & Genome-wide association study. The author has an hindex of 8, co-authored 9 publications receiving 1888 citations.
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Journal ArticleDOI
Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci.
Adrian Cortes,Johanna Hadler,J.P. Pointon,Philip Robinson,Tugce Karaderi,Paul Leo,Katie Cremin,Karena Pryce,Jessica Harris,Sang-Gug Lee,Kyung Bin Joo,Shim S-C.,Michael H. Weisman,Minghong Ward,Xiaodong Zhou,Garchon H-J.,Gilles Chiocchia,Johannes C. Nossent,Benedicte A. Lie,Øystein Førre,J. Tuomilehto,J. Tuomilehto,J. Tuomilehto,K. Laiho,Lei Jiang,Yu Liu,Xin Wu,Linda A. Bradbury,Dirk Elewaut,Ruben Burgos-Vargas,Simon Stebbings,Louise Appleton,Claire Farrah,J. Lau,Tony J. Kenna,Nigil Haroon,Manuel A. R. Ferreira,Jian Yang,J Mulero,José Luis Fernández-Sueiro,Miguel A. Gonzalez-Gay,Carlos López-Larrea,Panagiotis Deloukas,Peter Donnelly,Paul Bowness,Karl Gafney,Hill Gaston,Dafna D. Gladman,Dafna D. Gladman,Proton Rahman,Walter P. Maksymowych,Huji Xu,Crusius Jba.,I E van der Horst-Bruinsma,Chou C-T.,R. Valle-Oñate,Consuelo Romero-Sánchez,Inger Myrnes Hansen,Fernando Pimentel-Santos,Robert D. Inman,Vibeke Videm,Javier Martín,Maxime Breban,Maxime Breban,J. D. Reveille,David M. Evans,Kim T-H.,B P Wordsworth,Matthew A. Brown +68 more
TL;DR: In this paper, the authors used the Illumina Immunochip microarray to perform a case-control association study involving 10,619 individuals with ankylosing spondylitis (cases) and 15,145 controls.
Journal ArticleDOI
Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci
John D. Reveille,Anne Marie Sims,Patrick Danoy,David M. Evans,Paul Leo,J J Pointon,Rui Jin,Xiaodong Zhou,Linda A. Bradbury,L H Appleton,John C. Davis,Laura Diekman,Tracey Doan,Alison Dowling,Ran Duan,Emma L. Duncan,C Farrar,Johanna Hadler,David Harvey,Tugce Karaderi,R Mogg,Emma Pomeroy,Karena Pryce,Jacqueline Taylor,L. Savage,Panos Deloukas,Vasudev Kumanduri,Leena Peltonen,Susan M. Ring,Pamela Whittaker,Evgeny A. Glazov,Gethin P. Thomas,Walter P. Maksymowych,Robert D. Inman,Michael M. Ward,Millicent A. Stone,Millicent A. Stone,Michael H. Weisman,B. Paul Wordsworth,Matthew A. Brown,Matthew A. Brown +40 more
TL;DR: In this article, the authors conducted a genome-wide association study in 2,053 unrelated ankylosing spondylitis cases among people of European descent and 5,140 ethnically matched controls.
Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci
John D. Reveille,A. M. Sims,Patrick Danoy,David M. Evans,Paul Leo,J J Pointon,R. Jin,Xiaodong Zhou,Linda A. Bradbury,L H Appleton,J. C. Davis,Laura Diekman,Tracy Doan,Alison Dowling,Ran Duan,Emma L. Duncan,C Farrar,Johanna Hadler,David Harvey,Tugce Karaderi,R Mogg,Emma Pomeroy,Karena Pryce,Jenny C. Taylor,L. Savage,Panagiotis Deloukas,Vasudev Kumanduri,Leena Peltonen,S.M. Ring,Pamela Whittaker,Evgeny A. Glazov,Gethin P. Thomas,Walter P. Maksymowych,Robert D. Inman,M. M. Ward,Millicent A. Stone,Michael H. Weisman,B P Wordsworth,Matthew A. Brown +38 more
TL;DR: Four genetic loci associated with ankylosing spondylitis risk are reported and a major role for the interleukin (IL)-23 and IL-1 cytokine pathways in disease susceptibility is identified.
Journal ArticleDOI
Association of variants at 1q32 and STAT3 with ankylosing spondylitis suggests genetic overlap with Crohn's disease.
Patrick Danoy,Karena Pryce,Johanna Hadler,Linda A. Bradbury,C Farrar,J J Pointon,Michael E. Ward,Michael H. Weisman,John D. Reveille,B. Paul Wordsworth,Millicent A. Stone,Walter P. Maksymowych,Proton Rahman,Dafna D. Gladman,Robert D. Inman,Matthew A. Brown,Matthew A. Brown +16 more
TL;DR: This study identifies chr1q32 and STAT3 as ankylosing spondylitis susceptibility loci and further confirms association for IL23R and detects suggestive association with another 4 loci, suggesting common aetiopathogenic pathways for AS and Crohn's disease.
Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci
Adrian Cortes,Johanna Hadler,J.P. Pointon,Philip Robinson,Tugce Karaderi,Paul Leo,Katie Cremin,Karena Pryce,Jessica Harris,Sang-Gug Lee,Kyung Bin Joo,Seung-Cheol Shim,Michael H. Weisman,M. M. Ward,Xiaodong Zhou,Henri-Jean Garchon,Gilles Chiocchia,Johannes C. Nossent,Benedicte A. Lie,Øystein Førre,J. Tuomilehto,K. Laiho,Lei Jiang,Yu Liu,Xin Wu,Linda A. Bradbury,Dirk Elewaut,Ruben Burgos-Vargas,Simon Stebbings,L H Appleton,Claire Farrah,J. Lau,Tony J. Kenna,Nigil Haroon,Ferreira,Jian Yang,J Mulero,José Luis Fernández-Sueiro,Gonzalez-Gay,Carlos López-Larrea,Panagiotis Deloukas,Peter Donnelly,Paul Bowness,Karl Gafney,H. Gaston,Dafna D. Gladman,Proton Rahman,Walter P. Maksymowych,Huji Xu,J. B. A. Crusius,I E van der Horst-Bruinsma,Chung-Tei Chou,R. Valle-Oñate,Consuelo Romero-Sánchez,Inger Myrnes Hansen,Fernando Pimentel-Santos,Robert D. Inman,Vibeke Videm,Javier Martín,Maxime Breban,J. D. Reveille,David M. Evans,Tae-Hwan Kim,B P Wordsworth,Brown +64 more
TL;DR: Two ankylosing spondylitis–associated regions have now been identified encoding four aminopeptidases that are involved in peptide processing before major histocompatibility complex (MHC) class I presentation.