K
Karin Thevissen
Researcher at Katholieke Universiteit Leuven
Publications - 173
Citations - 13665
Karin Thevissen is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Candida albicans & Plant defensin. The author has an hindex of 49, co-authored 168 publications receiving 11610 citations. Previous affiliations of Karin Thevissen include Catholic University of Leuven.
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Journal ArticleDOI
Covalent immobilization of antimicrobial agents on titanium prevents Staphylococcus aureus and Candida albicans colonization and biofilm formation
Soňa Kucharíková,Evelien Gerits,Katrijn De Brucker,Annabel Braem,Katerina Čeh,Gregor Majdic,Tanja Spanic,Estera Pogorevc,Natalie Verstraeten,Hélène Tournu,Nicolas Delattin,Frédéric Impellizzeri,Martin Erdtmann,Annika Krona,Maria Lövenklev,Miomir Knezevic,Mirjam Fröhlich,Jef Vleugels,Maarten Fauvart,Wander Jose de Silva,Wander Jose de Silva,Katleen Vandamme,Jordi Garcia-Forgas,Bruno P. A. Cammue,Jan Michiels,Patrick Van Dijck,Karin Thevissen +26 more
TL;DR: These data demonstrate the clinical potential of covalently bound VAN and CAS on Ti to reduce microbial biofilm formation without jeopardizing osseointegration.
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Mining the genome of Arabidopsis thaliana as a basis for the identification of novel bioactive peptides involved in oxidative stress tolerance
Barbara De Coninck,Delphine Carron,Patrizia Tavormina,Lander Willem,David J. Craik,Christine Vos,Karin Thevissen,Janick Mathys,Bruno P. A. Cammue +8 more
TL;DR: The identification and characterization of OSIP108 confirms the validity of the high-throughput approach, based on tiling array analysis in A. thaliana and functional screening in yeast, to identify bioactive peptides.
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Antifungal plant defensins: increased insight in their mode of action as a basis for their use to combat fungal infections.
TL;DR: This review focuses on the structure, biological activity and antifungal mode of action of some well-characterized plant defensins, with particular attention to their fungal membrane target(s), their induced cell death mechanisms as well as their antibiofilm activity.
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Artemisinins, New Miconazole Potentiators Resulting in Increased Activity against Candida albicans Biofilms
Kaat De Cremer,Ellen Lanckacker,Tanne L. Cools,Marijke Bax,Katrijn De Brucker,Paul Cos,Bruno P. A. Cammue,Karin Thevissen +7 more
TL;DR: In this paper, the authors identify compounds that increase the activity of miconazole against Candida albicans biofilms and demonstrate that combining miconaxole and artesunate improves the antibiofilm activity.
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Antifungal activity of synthetic peptides derived from Impatiens balsamina antimicrobial peptides Ib-AMP1 and Ib-AMP4
Karin Thevissen,Isabelle E.J.A. François,Lolke Sijtsma,Aart van Amerongen,W.M.M. Schaaper,Rob H. Meloen,Truus Posthuma-Trumpie,Willem F. Broekaert,Bruno P. A. Cammue +8 more
TL;DR: It is shown that the all-D variants of Ib-AMP are as active on yeast and fungal strains as native peptides and could be improved by more than two-fold via replacement of amino acid residues by arginine or tryptophan, demonstrating the potential of the native Ib-AMPs to combat fungal infections.