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Katherine Plewes
Researcher at Mahidol University
Publications - 44
Citations - 1482
Katherine Plewes is an academic researcher from Mahidol University. The author has contributed to research in topics: Malaria & Acute kidney injury. The author has an hindex of 18, co-authored 40 publications receiving 1184 citations. Previous affiliations of Katherine Plewes include University of British Columbia & University of Calgary.
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Journal ArticleDOI
Spread of artemisinin-resistant Plasmodium falciparum in Myanmar: a cross-sectional survey of the K13 molecular marker
Kyaw Myo Tun,Mallika Imwong,Khin Maung Lwin,Aye A. Win,Tin Maung Hlaing,Thaung Hlaing,Khin Lin,Myat Phone Kyaw,Katherine Plewes,Katherine Plewes,M. Abul Faiz,Mehul Dhorda,Phaik Yeong Cheah,Phaik Yeong Cheah,Sasithon Pukrittayakamee,Elizabeth A. Ashley,Elizabeth A. Ashley,Tim J. Anderson,Shalini Nair,Marina McDew-White,Jennifer A. Flegg,Eric P. M. Grist,Philippe Allard Guérin,Richard J. Maude,Richard J. Maude,Frank Smithuis,Arjen M. Dondorp,Arjen M. Dondorp,Nicholas P. J. Day,Nicholas P. J. Day,François Nosten,Nicholas J. White,Nicholas J. White,Charles J. Woodrow,Charles J. Woodrow +34 more
TL;DR: Assessment of the spread of artemisinin-resistant P falciparum in Myanmar finds Artemisinin resistance extends across much of Myanmar, and Appropriate therapeutic regimens should be tested urgently and implemented comprehensively if spread of warfarin resistance to other regions is to be avoided.
Journal ArticleDOI
Iron Superoxide Dismutases Targeted to the Glycosomes of Leishmania chagasi Are Important for Survival
TL;DR: The results suggest that LcFeSODB plays an important role in parasite growth and survival by protecting glycosomes from superoxide toxicity.
Journal ArticleDOI
Cell-free hemoglobin mediated oxidative stress is associated with acute kidney injury and renal replacement therapy in severe falciparum malaria: an observational study
Katherine Plewes,Katherine Plewes,Katherine Plewes,Hugh W F Kingston,Hugh W F Kingston,Hugh W F Kingston,Aniruddha Ghose,Richard J. Maude,Richard J. Maude,M. Trent Herdman,Stije J. Leopold,Stije J. Leopold,Haruhiko Ishioka,Md. Mahtab Uddin Hasan,Md. Shafiul Haider,Shamsul Alam,Kim A. Piera,Prakaykaew Charunwatthana,Kamolrat Silamut,Tsin W. Yeo,Tsin W. Yeo,Md. Abul Faiz,Sue J. Lee,Sue J. Lee,Mavuto Mukaka,Mavuto Mukaka,Gareth D. H. Turner,Gareth D. H. Turner,Nicholas M. Anstey,L. Jackson Roberts,Nicholas J. White,Nicholas J. White,Nicholas P. J. Day,Nicholas P. J. Day,Md. Amir Hossain,Arjen M. Dondorp,Arjen M. Dondorp +36 more
TL;DR: Cell-free hemoglobin and lipid peroxidation are associated with acute kidney injury and disease severity in falciparum malaria, suggesting a pathophysiological role in renal tubular injury.
Journal ArticleDOI
Microvascular obstruction and endothelial activation are independently associated with the clinical manifestations of severe falciparum malaria in adults: an observational study
Joshua Hanson,Sue J. Lee,Sue J. Lee,Amir Hossain,Nicholas M. Anstey,Prakaykaew Charunwatthana,Richard J. Maude,Richard J. Maude,Hugh W. F. Kingston,Saroj K. Mishra,Sanjib Mohanty,Katherine Plewes,Kim A. Piera,Mahtab Uddin Hassan,Aniruddha Ghose,M. Aniruddha Faiz,Nicholas J. White,Nicholas J. White,Nicholas P. J. Day,Nicholas P. J. Day,Arjen M. Dondorp,Arjen M. Dondorp +21 more
TL;DR: Microvascular obstruction and systemic endothelial activation are independently associated with plasma lactate, the strongest predictor of death in adults with falciparum malaria, which supports the hypothesis that the two processes make an independent contribution to the pathogenesis and clinical manifestations of the disease.
Journal ArticleDOI
Malaria: What's New in the Management of Malaria?
TL;DR: The global burden of malaria remains high, with 216 million cases causing 445,000 deaths in 2016 despite first-line treatment with artemisinin-based combination therapy, according to the World Health Organization.