K
Katherine Sattler
Researcher at Heidelberg University
Publications - 19
Citations - 398
Katherine Sattler is an academic researcher from Heidelberg University. The author has contributed to research in topics: Cancer & Patch clamp. The author has an hindex of 8, co-authored 19 publications receiving 256 citations.
Papers
More filters
Journal ArticleDOI
Modeling Short QT Syndrome Using Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Ibrahim El-Battrawy,Huan Lan,Huan Lan,Lukas Cyganek,Zhihan Zhao,Xin Li,Fanis Buljubasic,Siegfried Lang,Gökhan Yücel,Katherine Sattler,Wolfram-Hubertus Zimmermann,Jochen Utikal,Thomas Wieland,Ursula Ravens,Martin Borggrefe,Xiaobo Zhou,Ibrahim Akin +16 more
TL;DR: Patient‐specific hiPSC‐CMs are able to recapitulate single‐cell phenotype features of SQTS and provide novel opportunities to further elucidate the cellular disease mechanism and test drug effects.
Journal ArticleDOI
Prevalence of cancer in Takotsubo cardiomyopathy: Short and long-term outcome.
Katherine Sattler,Ibrahim El-Battrawy,Siegfried Lang,Xunlei Zhou,Katja Schramm,Erol Tülümen,F. Kronbach,Susanne Röger,Michael Behnes,Jürgen Kuschyk,Martin Borggrefe,Ibrahim Akin +11 more
TL;DR: Prevalence of malignant diseases is high in TTC patients, and is a risk factor for worse outcome, and Screening for malignancies should be recommended in all patients presenting with TTC.
Journal ArticleDOI
Ion Channel Expression and Characterization in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Zhihan Zhao,Huan Lan,Huan Lan,Ibrahim El-Battrawy,Xin Li,Fanis Buljubasic,Katherine Sattler,Gökhan Yücel,Siegfried Lang,Malte Tiburcy,Wolfram-Hubertus Zimmermann,Lukas Cyganek,Jochen Utikal,Jochen Utikal,Thomas Wieland,Martin Borggrefe,Xiaobo Zhou,Xiaobo Zhou,Ibrahim Akin +18 more
TL;DR: The data demonstrate that most ion channels, which are present in healthy or diseased cardiomyocytes, exist in hiPSC-CMs and some of them contribute to action potential performance and are regulated by adrenergic stimulation.
Journal ArticleDOI
Estradiol protection against toxic effects of catecholamine on electrical properties in human-induced pluripotent stem cell derived cardiomyocytes.
Ibrahim El-Battrawy,Zhihan Zhao,Huan Lan,Huan Lan,Jan-Dierk Schünemann,Katherine Sattler,Fanis Buljubasic,Bence Patocskai,Xin Li,Gökhan Yücel,Siegfried Lang,Daniel Nowak,Lukas Cyganek,Karen Bieback,Jochen Utikal,Jochen Utikal,Wolfram-Hubertus Zimmermann,Ursula Ravens,Thomas Wieland,Martin Borggrefe,Xiaobo Zhou,Xiaobo Zhou,Ibrahim Akin +22 more
TL;DR: Estradiol has protective effects against catecholamine excess and hence reduction in estrogen level may increase the risk of acquired long QT syndrome in TTC.
Journal ArticleDOI
Ion Channel Dysfunctions in Dilated Cardiomyopathy in Limb-Girdle Muscular Dystrophy
Ibrahim El-Battrawy,Zhihan Zhao,Huan Lan,Xin Li,Gökhan Yücel,Siegfried Lang,Katherine Sattler,Jan-Dierk Schünemann,Wolfram-Hubertus Zimmermann,Lukas Cyganek,Jochen Utikal,Thomas Wieland,Karen Bieback,Ralf Bauer,Antonius Ratte,Regina Pribe-Wolferts,Kleopatra Rapti,Daniel Nowak,Janina Wittig,Dierk Thomas,Patrick Most,Hugo A. Katus,Ursula Ravens,Constanze Schmidt,Martin Borggrefe,Xiaobo Zhou,Oliver Müller,Ibrahim Akin +27 more
TL;DR: It is reported here that human induced pluripotent stem cell (hiPSC)–derived cardiomyocytes from a patient with LGMD2I and DCM associated with recurrent ventricular tachycardia displayed ion channel dysfunction and abnormality of calcium homeostasis.