K
Kathrin Sutter
Researcher at University of Duisburg-Essen
Publications - 48
Citations - 1065
Kathrin Sutter is an academic researcher from University of Duisburg-Essen. The author has contributed to research in topics: Immune system & Cytotoxic T cell. The author has an hindex of 14, co-authored 36 publications receiving 593 citations. Previous affiliations of Kathrin Sutter include Huazhong University of Science and Technology.
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Journal ArticleDOI
Susceptibility of SARS-CoV-2 to UV irradiation.
Christiane Silke Heilingloh,Ulrich Wilhelm Aufderhorst,Leonie Schipper,Ulf Dittmer,Oliver Witzke,Dongliang Yang,Xin Zheng,Kathrin Sutter,Mirko Trilling,Mira Alt,Eike Steinmann,Adalbert Krawczyk +11 more
TL;DR: Inactivation of Sars-CoV-2 by UVC irradiation constitutes a reliable method for disinfection purposes in health care facilities and for preparing SARS-Cov-2 material for research purpose.
Journal ArticleDOI
Impaired Cytotoxic CD8 + T Cell Response in Elderly COVID-19 Patients.
Jaana Westmeier,Krystallenia Paniskaki,Zehra Karaköse,Tanja Werner,Kathrin Sutter,Kathrin Sutter,Sebastian Dolff,Marvin Overbeck,Andreas Limmer,Jia Liu,Xin Zheng,Thorsten Brenner,Marc M. Berger,Oliver Witzke,Mirko Trilling,Mirko Trilling,Mengji Lu,Mengji Lu,Dongliang Yang,Nina Babel,Nina Babel,Timm H. Westhoff,Ulf Dittmer,Ulf Dittmer,Gennadiy Zelinskyy,Gennadiy Zelinskyy +25 more
TL;DR: The cytotoxic T cell potential was diminished, especially in effector memory and terminally differentiated effector CD8+ cells, showing that elderly patients have impaired cellular immunity against SARS-CoV-2.
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Guanylate-Binding Proteins 2 and 5 Exert Broad Antiviral Activity by Inhibiting Furin-Mediated Processing of Viral Envelope Proteins.
Elisabeth Braun,Dominik Hotter,Lennart Koepke,Fabian Zech,Rüdiger Groß,Konstantin M. J. Sparrer,Janis A. Müller,Christian K. Pfaller,Elena Heusinger,Rebecka Wombacher,Kathrin Sutter,Ulf Dittmer,Michael Winkler,Graham Simmons,Martin R. Jakobsen,Karl-Klaus Conzelmann,Stefan Pöhlmann,Jan Münch,Oliver T. Fackler,Frank Kirchhoff,Daniel Sauter +20 more
TL;DR: Collectively, the results show that GPB2/5 exert broad antiviral activity by suppressing the activity of the virus-dependency factor furin.
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An advanced BLT-humanized mouse model for extended HIV-1 cure studies.
Kerry J. Lavender,Craig S. Pace,Kathrin Sutter,Ronald J. Messer,Dakota L. Pouncey,Nathan W. Cummins,Sekar Natesampillai,Jim Zheng,Joshua Goldsmith,Marek Widera,Erik Van Dis,Katie Phillips,Brent Race,Ulf Dittmer,George Kukolj,Kim J. Hasenkrug +15 more
TL;DR: HIV-1 latency can be maintained in TKO-BLT mice over extended periods on ART and rapid viral rebound occurs following therapy removal, providing sufficient time to examine the decay kinetics of the latent reservoir as well as observe delays in recrudescence in HIV-1 cure studies.
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Hepatitis B virus sensitivity to interferon‐α in hepatocytes is more associated with cellular interferon response than with viral genotype
Fang Shen,Fang Shen,Yaming Li,Yang Wang,Vitina Sozzi,Peter Revill,Jiangxia Liu,Lu Gao,Guang Yang,Mengji Lu,Kathrin Sutter,Ulf Dittmer,Jieliang Chen,Zhenghong Yuan +13 more
TL;DR: In the cell–culture–based HBV infection models, the sensitivity of HBV to IFN‐α in hepatocytes is determined more by the cell‐intrinsic IFN response than by viral genotype, and improvement of theIFN response in HepG2‐NTCP cells promotes the efficacy of IFN•α against HBV.