K
Kathryn C.B. Tan
Researcher at University of Hong Kong
Publications - 172
Citations - 6003
Kathryn C.B. Tan is an academic researcher from University of Hong Kong. The author has contributed to research in topics: Diabetes mellitus & Medicine. The author has an hindex of 35, co-authored 133 publications receiving 5072 citations. Previous affiliations of Kathryn C.B. Tan include Queen Mary University of London & Li Ka Shing Faculty of Medicine, University of Hong Kong.
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Journal ArticleDOI
Testosterone selectively reduces the high molecular weight form of adiponectin by inhibiting its secretion from adipocytes
Aimin Xu,Aimin Xu,Kok Weng Chan,Ruby L. C. Hoo,Yu Wang,Yu Wang,Kathryn C.B. Tan,Jialiang Zhang,Baoying Chen,Michael C. Lam,Cynthia A. Tse,Garth J. S. Cooper,Karen S.L. Lam +12 more
TL;DR: The selective inhibition of HMW adip onectin by testosterone might contribute to the sex dimorphism of adiponectin in terms of its oligomeric complex distribution and could partly explain why men have higher risk to insulin resistance and atherosclerosis than women.
Journal ArticleDOI
Hypoadiponectinemia is associated with impaired endothelium-dependent vasodilation.
Kathryn C.B. Tan,Aimin Xu,Wing Sun Chow,Michael C. Lam,Victor H. G. Ai,Sidney Tam,Karen S.L. Lam +6 more
TL;DR: Low plasma adiponectin level is associated with impaired endothelium-dependent vasodilation, and the association is independent of diabetes mellitus.
Journal ArticleDOI
Advanced Glycation End Products and Endothelial Dysfunction in Type 2 Diabetes
Kathryn C.B. Tan,Wing Sun Chow,Victor H. G. Ai,Christine N. Metz,Richard Bucala,Karen S.L. Lam +5 more
TL;DR: Increased serum concentrations of AGEs in patients with type 2 diabetes is associated with endothelial dysfunction, independent of other cardiovascular risk factors, and further studies to determine whether treatment targeting AGES will lead to an amelioration of endothelial function are warranted.
Journal ArticleDOI
Hypoadiponectinemia as a Predictor for the Development of Hypertension. A 5-Year Prospective Study
Wing Sun Chow,Bernard M.Y. Cheung,Annette W.K. Tso,Aimin Xu,Nelson M.S. Wat,Carol H.Y. Fong,Liza H. Y. Ong,Sidney Tam,Kathryn C.B. Tan,Edward D Janus,Tai Hing Lam,Karen S.L. Lam +11 more
TL;DR: The data suggest that hypoadiponectinaemia may be involved in the pathogenesis of hypertension in humans, and the relationship of serum adiponectin with the development of hypertension was investigated in a nested case–control study.
Journal ArticleDOI
Prevalence, Treatment, and Control of Diagnosed Diabetes in the U.S. National Health and Nutrition Examination Survey 1999–2004
Kwok Leung Ong,Bernard M.Y. Cheung,Louisa Y.F. Wong,Nelson M.S. Wat,Kathryn C.B. Tan,Karen S.L. Lam +5 more
TL;DR: The increases in percentages of people with diabetes achieving glycemic and blood pressure targets are encouraging, although there is room for improvement.