K
Kazuya Yoshinaga
Researcher at RMIT University
Publications - 7
Citations - 403
Kazuya Yoshinaga is an academic researcher from RMIT University. The author has contributed to research in topics: Lectin & Cellular differentiation. The author has an hindex of 4, co-authored 7 publications receiving 351 citations.
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Journal ArticleDOI
Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation.
Tomohiko Murakami,Atsushi Saito,Shin-ichiro Hino,Shinichi Kondo,Soshi Kanemoto,Kazuyasu Chihara,Hiroshi Sekiya,Kenji Tsumagari,Kimiko Ochiai,Kazuya Yoshinaga,Masahiro Saitoh,Riko Nishimura,Toshiyuki Yoneda,Ikuyo Kou,Tatsuya Furuichi,Shiro Ikegawa,Masahito Ikawa,Masaru Okabe,Akio Wanaka,Kazunori Imaizumi +19 more
TL;DR: The studies show that OASIS is critical for bone formation through the transcription of Col1a1 and the secretion of bone matrix proteins, and they reveal a new mechanism by which ER stress-induced signalling mediates bone formation.
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Shikonin, dually functions as a proteasome inhibitor and a necroptosis inducer in multiple myeloma cells
Naoko Wada,Yawara Kawano,Shiho Fujiwara,Yoshitaka Kikukawa,Yutaka Okuno,Masayoshi Tasaki,Mitsuharu Ueda,Yukio Ando,Kazuya Yoshinaga,Masaki Ri,Shinsuke Iida,Takayuki Nakashima,Yukimasa Shiotsu,Hiroaki Mitsuya,Hiroyuki Hata +14 more
TL;DR: The present data show for the first time that SHK induces cell death in MM cells, and support the use of SHK as a potential therapeutic agent for MM.
Journal ArticleDOI
Viable offspring obtained from Prm1-deficient sperm in mice
Naoki Takeda,Kazuya Yoshinaga,Kenryo Furushima,Kazufumi Takamune,Zhenghua Li,Shin Ichi Abe,Shin Aizawa,Ken Ichi Yamamura +7 more
TL;DR: The result suggests that sperm lacking Prm1 can generate offspring despite being abnormally shaped and having destabilised DNA, decondensed chromatin and a reduction in mitochondrial membrane potential, and these mice showed little derangement of expression profiles.
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Cell- and region-specific expression of sugar chains in the mouse epididymal epithelium using lectin histochemistry combined with immunohistochemistry
TL;DR: Findings indicate that the selectivity in lectin reactivity for distinct cell types and segment-dependent staining in the epididymis may be related to cellular and regional differences in function.
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Cytokeratin localization and basal cell differentiation in the epididymal epithelium during postnatal development of the mouse
TL;DR: The expression and localization of cytokeratins (CKs) in the epididymal epithelium during postnatal development of the mouse showed that, in adult mice, CK5 and CK14 were exclusively expressed in the cytoplasm of basal cells.