K
Keita Morikane
Researcher at Yamagata University
Publications - 74
Citations - 1213
Keita Morikane is an academic researcher from Yamagata University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 16, co-authored 61 publications receiving 1022 citations. Previous affiliations of Keita Morikane include National Institutes of Health & Tohoku University.
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Journal ArticleDOI
Blockade of the Stromal Cell–Derived Factor-1/CXCR4 Axis Attenuates In vivo Tumor Growth by Inhibiting Angiogenesis in a Vascular Endothelial Growth Factor–Independent Manner
Bayasi Guleng,Keisuke Tateishi,Miki Ohta,Fumihiko Kanai,Amarsanaa Jazag,Hideaki Ijichi,Yasuo Tanaka,Miwa Washida,Keita Morikane,Yasushi Fukushima,Takao Yamori,Takashi Tsuruo,Takao Kawabe,Makoto Miyagishi,Kazunari Taira,Masataka Sata,Masao Omata +16 more
TL;DR: The data indicate that the SDF-1/CXCR4 pathway might be a general target for anticancer strategies and that blocking this system could be cooperatively effective in combination with other antiangiogenic therapies, such as blockade of VEGF.
Journal Article
Tolerance and immunity to MUC1 in a human MUC1 transgenic murine model
Richard M. Tempero,Keita Morikane,Michelle L. VanLith,Sandra J. Gendler,Michael A. Hollingsworth +4 more
TL;DR: Data suggest that endogenous expression of MUC1 protein by M UC1 transgenic mice induces T-cell tolerance to stimulation by MUC2, and will facilitate the investigation of anti-MUC1 immunotherapy formulations.
Journal ArticleDOI
APSIC guide for prevention of Central Line Associated Bloodstream Infections (CLABSI)
Moi Lin Ling,Anucha Apisarnthanarak,Namita Jaggi,Glenys Harrington,Keita Morikane,Le Thi Anh Thu,Patricia T.Y. Ching,Victoria Villanueva,Zhiyong Zong,Jae Sim Jeong,Chun-Ming Lee +10 more
TL;DR: A surveillance program is recommended to monitor outcomes and adherence to evidence-based central line insertion and maintenance practices (compliance rate) and identify quality improvement opportunities and strategically targeting interventions for the reduction of CLABSI.
Journal ArticleDOI
The human homologue of the RNA polymerase II-associated factor 1 (hPaf1), localized on the 19q13 amplicon, is associated with tumorigenesis.
Nicolas Moniaux,C. Nemos,Bruno M. Schmied,Subhash C. Chauhan,Shonali Deb,Keita Morikane,Amit Choudhury,Michelle L. VanLith,Marie E. Sutherlin,James M. Sikela,Michael A. Hollingsworth,Surinder K. Batra +11 more
TL;DR: Evidence is presented that the overexpression of PD2 in the NIH 3T3 cells result in enhanced growth rates in vitro and tumor formation in vivo, and it is demonstrated that PD2 is a nuclear 80 kDa protein, which interacts with RNA polymerase II.
Journal Article
CD4+ Lymphocytes Provide MUC1-Specific Tumor Immunity In Vivo That Is Undetectable In Vitro and Is Absent in MUC1 Transgenic Mice
Richard M. Tempero,Michelle L. VanLith,Keita Morikane,Gerald J. Rowse,Sandra J. Gendler,Michael A. Hollingsworth +5 more
TL;DR: Tumor immunity in vivo was characterized by an adoptive transfer method to evaluate the degree of MUC1 or non-MUC1 tumor immunity in wt or M UC1.Tg mice, indicating that tumor immune responses mediated by Muc1-specific CD4+ lymphocytes spare nontransformed epithelia-expressing MUC2.