K
Ken Arai
Researcher at Harvard University
Publications - 163
Citations - 9089
Ken Arai is an academic researcher from Harvard University. The author has contributed to research in topics: Oligodendrocyte & White matter. The author has an hindex of 50, co-authored 149 publications receiving 7597 citations. Previous affiliations of Ken Arai include Autonomous University of Barcelona & Massachusetts Institute of Technology.
Papers
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Journal ArticleDOI
Optical magnetic imaging of living cells
D. Le Sage,Ken Arai,David Glenn,Stephen J. DeVience,Linh Pham,Lilah Rahn-Lee,Mikhail D. Lukin,Amir Yacoby,Arash Komeili,Ronald L. Walsworth +9 more
TL;DR: This work demonstrates magnetic imaging of living cells (magnetotactic bacteria) under ambient laboratory conditions and with sub-cellular spatial resolution, using an optically detected magnetic field imaging array consisting of a nanometre-scale layer of nitrogen–vacancy colour centres implanted at the surface of a diamond chip.
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Lipoprotein receptor-mediated induction of matrix metalloproteinase by tissue plasminogen activator.
Xiaoying Wang,Sun-Ryung Lee,Ken Arai,Seong-Ryong Lee,Kiyoshi Tsuji,G. William Rebeck,Eng H. Lo +6 more
TL;DR: It is shown that tPA upregulates MMP-9 in cell culture and in vivo, and Targeting the tPA-LRP signaling pathway in brain may offer new approaches for decreasing neurotoxicity and improving stroke therapy.
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Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue
Sava Sakadžić,Emmanuel Roussakis,Mohammad A. Yaseen,Emiri T. Mandeville,Vivek J. Srinivasan,Ken Arai,Svetlana Ruvinskaya,Anna Devor,Anna Devor,Eng H. Lo,Sergei A. Vinogradov,David A. Boas +11 more
TL;DR: This work reports to their knowledge the first practical in vivo two-photon high-resolution pO2 measurements in small rodents' cortical microvasculature and tissue, made possible by combining an optimized imaging system with a two-Photon–enhanced phosphorescent nanoprobe.
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Induction of human IgE synthesis requires interleukin 4 and T/B cell interactions involving the T cell receptor/CD3 complex and MHC class II antigens.
TL;DR: The results suggest that at least two, possibly synergizing, signals are required for the T cell-dependent induction of IgE synthesis by B cells: one signal is delivered by cognate T/B cell interaction, the other by Tcell-derived IL-4.
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Pathophysiologic cascades in ischemic stroke.
TL;DR: The basics of ischemic cascades after stroke are summarized, covering neuronal death mechanisms, white matter pathophysiology, and inflammation with an emphasis on microglia.