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Ken-ichi Isobe

Researcher at Nagoya University

Publications -  294
Citations -  18597

Ken-ichi Isobe is an academic researcher from Nagoya University. The author has contributed to research in topics: Antigen & Cytotoxic T cell. The author has an hindex of 48, co-authored 293 publications receiving 16715 citations. Previous affiliations of Ken-ichi Isobe include Nagoya Women's University & Shubun University.

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Journal ArticleDOI

Augmentation of Antibody Responses of Mice to Inhaled Protein Antigens by Simultaneously Inhaled Bacterial Lipopolysaccharides

Kenji Mizoguchi, +7 more
- 01 Oct 1986 - 
TL;DR: The results prove for the first time that inhaled LPS displays a definite adjuvant action on antibody responses to inhaled antigens.
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Oncogene-linked in situ immunotherapy of pre-B lymphoma arising in Eμ/ret transgenic mice

Masatoshi Ichihara, +9 more
- 01 Apr 1995 - 
TL;DR: Interestingly, this immunisation enabled the E mu/ret TGM to survive longer than the non-immunised control group (P < 0.05), and 2 of 11 transgenic mice receiving such immunisation were free from both macroscopic and microscopic tumours at the time when all of the 12 non-IMmunisation control TGM had died from their tumour.
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Dynamics of cytotoxic T lymphocyte precursors in vivo assessed by change in the radiation sensitivity. Evidence for development of radiation-sensitive memory cells without clonal expansion.

Yoshinori Hasegawa, +9 more
- 01 Jul 1988 - 
TL;DR: The dynamics of cytotoxic T lymphocyte precursors in mice injected with allogeneic spleen cells was studied and showed that helper cells whose activity was replaceable with IL‐2 (IL‐2‐producing cells) were functionally more radiation‐sensitive than CTL‐p in unprimed mice.
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Inhibition of Human Complement-Dependent Cell Lysis by Bovine Aortic Endothelial Cells Transfected with Membrane-Bound Complement-Regulatory Factor (DAF and HRF20) Gene Using a Retroviral Vector

Shuji Hayashi, +6 more
- 01 Jan 1996 - 
TL;DR: These data demonstrate that xenograft EC transfected with DAF or HRF20 cDNA using retroviral vector are protected from complement-dependent cell lysis.
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Modulation of the secondary antibody response of murine lymphocytes to sheep red blood cells in vitro by neuraminidase and exoglycosidases

Makoto Nakamura, +8 more
- 01 Aug 1991 - 
TL;DR: It is suggested from these results that sialylated complex type oligosaccharides on antigen-primed T cells play a critical role in their suppressor activity.