K
Ken-ichi Isobe
Researcher at Nagoya University
Publications - 294
Citations - 18597
Ken-ichi Isobe is an academic researcher from Nagoya University. The author has contributed to research in topics: Antigen & Cytotoxic T cell. The author has an hindex of 48, co-authored 293 publications receiving 16715 citations. Previous affiliations of Ken-ichi Isobe include Nagoya Women's University & Shubun University.
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Journal ArticleDOI
Intra-bone marrow bone marrow transplantation rejuvenates the B-cell lineage in aged mice.
TL;DR: Intra‐bone marrow bone marrow transplantation (IBM‐BMT) of young marrow cells including both hematopoietic stem cells and bone marrow stromal cells reversed the reduction of pro‐B cells and pre-B cells.
Journal Article
Rat mesangial cells actively produce phosphatidylinositol-anchored Thy-1.
Toshio Miyata,Ken-ichi Isobe,Reiko Inagi,R. Taguchi,H. Ikezawa,Ichiro Takai,Yoshiro Fujita,Takashi Iwamoto,Takaaki Hasegawa,Osamu Oda,N. Yamanaka,Satoshi Sugiyama,Kei-ichiro Maeda,Kazumasa Yamada,Izumi Nakashima +14 more
TL;DR: It is provided evidence that the mesangial cells of rat kidney glomeruli express Thy-1 as a phosphatidylinositol-anchored protein.
Journal Article
Identification and Characterization of a Unique Tumor-associated Surface Antigen on L1210 Leukemia Cells Recognized by Semisyngeneic Antisera
Takashi Yokochi,Kohei Kawashima,Izumi Nakashima,Fumihiko Nagase,Ken-ichi Isobe,Eiichi Nagura,Kazumasa Yamada,Toshiaki Miyadai,Yoshinobu Kimura +8 more
TL;DR: The tumor-associated surface antigen on L 1210 leukemia cells was studied by immunofluorescence staining and immunoprecipitation and the biological significance of the L1210-specific cell surface antigen is discussed.
Journal ArticleDOI
GADD34 suppresses wound healing by upregulating expression of myosin IIA.
Chie Tanaka,Sachiko Ito,Naomi Nishio,Yasuhiro Kodera,Hidetoshi Sakurai,Haruhiko Suzuki,Akimasa Nakao,Ken-ichi Isobe +7 more
TL;DR: Results indicate that GADD34 negatively regulates cell migration in wound healing via expression of myosin IIA, and in vitro and in vivo wound healing experiments indicate this.
Journal ArticleDOI
GADD34 Promotes Tumor Growth by Inducing Myeloid-derived Suppressor Cells.
TL;DR: These findings provide a promising strategy for targeting GADD34 activity in order to inhibit tumor growth and resulted in decreased accumulation of MDSCs and T-cells.