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Ken-ichi Isobe

Researcher at Nagoya University

Publications -  294
Citations -  18597

Ken-ichi Isobe is an academic researcher from Nagoya University. The author has contributed to research in topics: Antigen & Cytotoxic T cell. The author has an hindex of 48, co-authored 293 publications receiving 16715 citations. Previous affiliations of Ken-ichi Isobe include Nagoya Women's University & Shubun University.

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Journal Article

Determination of the molecular nature and cellular localization of Thy-1 in human renal tissue.

TL;DR: Data demonstrate for the first time the production of human Thy-1 as a PI-anchored protein with a unique cellular location in human renal tissue.
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Therapeutic efficacy of bone marrow‐derived mononuclear cells in diabetic polyneuropathy is impaired with aging or diabetes

TL;DR: The effects of BM‐MNCs transplantation in diabetic polyneuropathy is investigated using BM‐ MNCs derived from adult (16‐week‐old) diabetic (AD), adult non‐diabetic (AN) or young (8‐week-old) non-di diabetic (YN) rats.
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Kupffer cells cytotoxicity against hepatoma cells is related to nitric oxide.

TL;DR: Kupffer cell-mediated cytotoxicity was paralleled to the amount of nitric oxide and was abolished by the addition of NG-monomethyl-L-arginine.
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Inhibitory effect of bestatin on the growth of human lymphocytes.

TL;DR: Growth inhibitory and growth stimulatory effect of bestatin was found to be independent of adherent cells (macrophage and dendritic cell), indicatory directly working to T or B lymphocytes, and enhanced the Con A, LPS-induced mitogenicity of murine lymphocytes.
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Characterization of the Growth Factor Activity of Amniotic Fluid on Cells from Hematopoietic and Lymphoid Organs of Different Life Stages

TL;DR: It is suggested that MAF contains growth factors for hematopoietic stem cells but not for either mature or immature T lymphocytes, and the MAF activity was further shown to be partially and cell type‐dependently antagonized by TNF‐α and TGF‐β.