K
Ken-ichi Nakahama
Researcher at Tokyo Medical and Dental University
Publications - 69
Citations - 2948
Ken-ichi Nakahama is an academic researcher from Tokyo Medical and Dental University. The author has contributed to research in topics: Osteoclast & Gene expression. The author has an hindex of 24, co-authored 66 publications receiving 2679 citations. Previous affiliations of Ken-ichi Nakahama include University of Pennsylvania & Kindai University.
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Journal ArticleDOI
A transcription factor response element for gene expression during circadian night
Hiroki R. Ueda,Wenbin Chen,Akihito Adachi,Hisanori Wakamatsu,Satoko Hayashi,Tomohiro Takasugi,Mamoru Nagano,Ken-ichi Nakahama,Yutaka Suzuki,Sumio Sugano,Masamitsu Iino,Yasufumi Shigeyoshi,Seiichi Hashimoto +12 more
TL;DR: The role of the Rev-ErbA/ROR response element in gene expression during circadian night is demonstrated, which is in phase with Bmal1 and in antiphase to Per2 oscillations.
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An Abrupt Shift in the Day/Night Cycle Causes Desynchrony in the Mammalian Circadian Center
Mamoru Nagano,Akihito Adachi,Ken-ichi Nakahama,Toru Nakamura,Masako Tamada,Elizabeth L. Meyer-Bernstein,Amita Sehgal,Yasufumi Shigeyoshi +7 more
TL;DR: It is demonstrated that an abrupt shift in the light/dark (LD) cycle disrupts the synchronous oscillation of circadian components in the rat SCN and dissociation and slow resynchronization of endogenous oscillators within the SCN after an LD cycle shift suggests a mechanism for the physiological symptoms that constitute jet lag.
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Cellular communications in bone homeostasis and repair
TL;DR: The role of cell–cell communication in bone remodeling is discussed and osteoblasts differentiate to osteocytes in bone or to bone lining cells on bone surfaces, which regenerated as new bone.
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Cholesteryl group- and acryloyl group-bearing pullulan nanogel to deliver BMP2 and FGF18 for bone tissue engineering
Masako Fujioka-Kobayashi,Masato S. Ota,Asako Shimoda,Asako Shimoda,Ken-ichi Nakahama,Kazunari Akiyoshi,Kazunari Akiyoshi,Youji Miyamoto,Sachiko Iseki +8 more
TL;DR: It is indicated that the CHPOA/hydrogel system can successfully deliver two different proteins to the bone defect to induce effective bone repair and might be a step towards efficient bone tissue engineering.
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Isolation of multipotent stem cells from adult rat periodontal ligament by neurosphere-forming culture system.
Wanida Techawattanawisal,Ken-ichi Nakahama,Motohiro Komaki,Mayumi Abe,Yuzo Takagi,Ikuo Morita +5 more
TL;DR: Data indicate that PDL-derived spheres contained multipotent adult stem cells capable of differentiating into both neural and mesodermal progeny.