K
Kenneth H. Williams
Researcher at Lawrence Berkeley National Laboratory
Publications - 268
Citations - 12458
Kenneth H. Williams is an academic researcher from Lawrence Berkeley National Laboratory. The author has contributed to research in topics: Biogeochemical cycle & Geobacter. The author has an hindex of 53, co-authored 248 publications receiving 10154 citations. Previous affiliations of Kenneth H. Williams include California Institute of Technology & University of California, Berkeley.
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Unusual biology across a group comprising more than 15% of domain Bacteria
Christopher T. Brown,Laura A. Hug,Brian C. Thomas,Itai Sharon,Cindy J. Castelle,Andrea Singh,Michael J. Wilkins,Kelly C. Wrighton,Kenneth H. Williams,Jillian F. Banfield +9 more
TL;DR: This work reconstructed 8 complete and 789 draft genomes from bacteria representing >35 phyla and documented features that consistently distinguish these organisms from other bacteria, infer that this group, which may comprise >15% of the bacterial domain, has shared evolutionary history, and describe it as the candidate phyla radiation (CPR).
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Thousands of microbial genomes shed light on interconnected biogeochemical processes in an aquifer system
Karthik Anantharaman,Christopher T. Brown,Laura A. Hug,Itai Sharon,Cindy J. Castelle,Alexander J. Probst,Brian C. Thomas,Andrea Singh,Michael J. Wilkins,Ulas Karaoz,Eoin L. Brodie,Kenneth H. Williams,Susan S. Hubbard,Jillian F. Banfield,Jillian F. Banfield +14 more
TL;DR: Terabase-scale cultivation-independent metagenomics is applied to aquifer sediments and groundwater and 2,540 draft-quality, near-complete and complete strain-resolved genomes are reconstructed, finding that few organisms within the community can conduct multiple sequential redox transformations.
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Fermentation, hydrogen, and sulfur metabolism in multiple uncultivated bacterial phyla.
Kelly C. Wrighton,Brian C. Thomas,Itai Sharon,Christopher S. Miller,Cindy J. Castelle,Nathan C Verberkmoes,Michael J. Wilkins,Robert L. Hettich,Mary S. Lipton,Kenneth H. Williams,Philip E. Long,Jillian F. Banfield,Jillian F. Banfield +12 more
TL;DR: This article uncovered metabolic characteristics for members of these phyla, and a new lineage, PER, via cultivation-independent recovery of 49 partial to near-complete genomes from an acetate-amended aquifer.
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Genomic Expansion of Domain Archaea Highlights Roles for Organisms from New Phyla in Anaerobic Carbon Cycling
Cindy J. Castelle,Kelly C. Wrighton,Brian C. Thomas,Laura A. Hug,Christopher T. Brown,Michael J. Wilkins,Kyle R. Frischkorn,Susannah G. Tringe,Andrea Singh,Lye Meng Markillie,Ronald C. Taylor,Kenneth H. Williams,Jillian F. Banfield +12 more
TL;DR: This study sequenced DNA from complex sediment and planktonic consortia from an aquifer adjacent to the Colorado River and reconstructed the first complete genomes for Archaea using cultivation-independent methods, which dramatically expand genomic sampling of the domain Archaea and clarify taxonomic designations within a major superphylum.
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Community genomic analyses constrain the distribution of metabolic traits across the Chloroflexi phylum and indicate roles in sediment carbon cycling
Laura A. Hug,Cindy J. Castelle,Kelly C. Wrighton,Brian C. Thomas,Itai Sharon,Kyle R. Frischkorn,Kenneth H. Williams,Susannah G. Tringe,Jillian F. Banfield +8 more
TL;DR: The potential roles of Chloroflexi in sediment carbon cycling beyond organohalide respiration are expanded to include respiration of sugars, fermentation, CO2 fixation, and acetogenesis with ATP formation by substrate-level phosphorylation.