Kerrie M. Sanders

TL;DR: Among older community-dwelling women, annual oral administration of high-dose cholecalciferol resulted in an increased risk of falls and fractures.

TL;DR: BMD and clinical risk factors predict hip and other osteoporotic fractures with higher specificity and sensitivity than either alone and provide the basis for the integrated use of validated Clinical risk factors in men and women to aid in fracture risk prediction.

TL;DR: Benefits at the highest level of vitamin D intake were fairly consistent across subgroups defined by age group, type of dwelling, baseline 25-hydroxyvitamin D level, and additional calcium intake, and high-dose vitamin D supplementation was somewhat favorable in the prevention of hip fracture and any nonvertebral fracture in persons 65 years of age or older.

TL;DR: There is good evidence that vitamin D plus calcium supplementation effectively reduces fractures and falls in older men and women and could play a role in the prevention of some disease states.

TL;DR: Fracture rates in Australia appeared high, particularly among the older age strata, compared with retrospective ascertainment in other populations and the substantial health burden imposed by age-related fractures, particularly hip fractures, will continue to escalate in both women and men.