Kevin Bailey

TL;DR: This work has engineer a very potent high-affinity VEGF blocker that has markedly enhanced pharmacokinetic properties and effectively suppresses tumor growth and vascularization in vivo, resulting in stunted and almost completely avascular tumors.

TL;DR: A generally applicable method to create very high-affinity blockers called 'cytokine traps' consisting of fusions between the constant region of IgG and the extracellular domains of two distinct cytokine receptor components involved in binding the cytokine.

TL;DR: It is shown that angiopoietin-1 has a modular structure unlike any previously characterized growth factor, and its antagonist activity seems to be a subtle property encoded in its receptor-binding domain.

TL;DR: In this article, the authors used a laser-based atom-counting method to measure 81 Kr/Kr in deep groundwater from the Nubian Aquifer (Egypt).

TL;DR: In this article, the authors report on the first of several experimental upgrades to improve the statistical sensitivity of their atomic electric dipole moments (EDM) measurements by orders of magnitude and evaluate systematic effects that contribute to current and future levels of experimental sensitivity.