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Kevin Squire
Researcher at University of California, Los Angeles
Publications - 9
Citations - 16722
Kevin Squire is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Population bottleneck & Domestication. The author has an hindex of 6, co-authored 9 publications receiving 11497 citations.
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Landscape genomic analysis of candidate genes for climate adaptation in a California endemic oak, Quercus lobata
Victoria L. Sork,Kevin Squire,Paul F. Gugger,Stephanie E. Steele,Eric D. Levy,Andrew J. Eckert +5 more
TL;DR: The authors used DNA from 45 individuals from 13 localities across the species' range, sequenced portions of 40 candidate genes related to budburst/flowering, growth, osmotic stress, and temperature stress.
Journal ArticleDOI
Dusp6 is a genetic modifier of growth through enhanced ERK activity
Andy H. Vo,Kayleigh A. Swaggart,Anna Woo,Quan Q. Gao,Alexis R. Demonbreun,Katherine S. Fallon,Mattia Quattrocelli,Michele Hadhazy,Patrick Page,Zugen Chen,Ascia Eskin,Kevin Squire,Stanley F. Nelson,Elizabeth M. McNally +13 more
TL;DR: DUSP6 is identified as an important regulator of ERK activity in the setting of muscle growth and muscular dystrophy by identifying the Met62Ile substitution in the dual-specificity phosphatase 6 (Dusp6) gene from the DBA/2 J (D2) mouse strain.
Posted Content
Genome Sequencing Highlights Genes Under Selection and the Dynamic Early History of Dogs
Adam H. Freedman,Rena M. Schweizer,Ilan Gronau,Eunjung Han,Diego Ortega-Del Vecchyo,Pedro Silva,Marco Galaverni,Zhenxin Fan,Peter Marx,Belen Lorente-Galdos,Holly C. Beale,Oscar Ramirez,Farhad Hormozdiari,Can Alkan,Carles Vilà,Kevin Squire,Eli Geffen,Josip Kusak,Adam R. Boyko,Heidi G. Parker,Clarence Lee,Vasisht Tadigotla,Adam Siepel,Carlos Bustamante,Timothy T. Harkins,Stanley F. Nelson,Elaine A. Ostrander,Tomas Marques-Bonet,Robert K. Wayne,John Novembre +29 more
TL;DR: It is found that surprisingly, none of the extant wolf lineages from putative domestication centers are more closely related to dogs, and the sampled wolves instead form a sister monophyletic clade, suggesting a re-evaluation of past hypotheses of dog origin is necessary.
An integrated map of structural variation in 2,504 human genomes_supplement
Sudmant Ph,Tobias Rausch,Gardner Ej,Handsaker Re,Alexej Abyzov,John Huddleston,Yujun Zhang,Kenny Ye,Goo Jun,M. Hsi Yang Fritz,Konkel Mk,Ankit Malhotra,Stütz Am,Xinghua Shi,F. Paolo Casale,Jieming Chen,Fereydoun Hormozdiari,Gargi Dayama,Ken Chen,Maika Malig,Chaisson Mj,Klaudia Walter,Sascha Meiers,Seva Kashin,Erik Garrison,Adam Auton,Lam Hy,X. Jasmine Mu,Can Alkan,Danny Antaki,T. Bae,Eliza Cerveira,P. Chines,Zechen Chong,Laura Clarke,Elif Dal,Li Ding,S. Emery,Xian Fan,Madhusudan Gujral,Fatma Kahveci,Kidd Jm,Yu Kong,Lameijer Ew,Shane A. McCarthy,Paul Flicek,Gibbs Ra,Gabor T. Marth,Mason Ce,Androniki Menelaou,Muzny Dm,Nelson Bj,Amina Noor,Parrish Nf,M. Pendleton,Andrew Quitadamo,Benjamin Raeder,Schadt Ee,Mallory Romanovitch,A. Schlattl,R. Sebra,Shabalin Aa,A. Untergasser,Walker Ja,M. Wang,Fuli Yu,Chengsheng Zhang,Jing Zhang,X. Zheng Bradley,W. Zhou,T. Zichner,Jonathan Sebat,Batzer Ma,McCarroll Sa,Abecasis Gr,Altshuler Dm,Durbin Rm,Bentley Dr,Aravinda Chakravarti,Clark Ag,Peter Donnelly,Eichler Ee,Gabriel Sb,Green Ed,Hurles Me,Knoppers Bm,Korbel Jo,Lander Es,Charles Kai-Wu Lee,Hans Lehrach,Mardis Er,Marth Gt,McVean Ga,Nickerson Da,Schmidt Jp,Sherry St,Jun Wang,Wilson Rk,Eric Boerwinkle,Harsha Doddapaneni,Yi Han,Viktoriya Korchina,Christie Kovar,Sandra J. Lee,Donna M. Muzny,Reid Jg,Yiming Zhu,Yuqi Chang,Qiang Feng,Xiaodong Fang,Xiaosen Guo,Min Jian,Hui Jiang,Xin Jin,Tianming Lan,Guoqing Li,Jingxiang Li,Yun Li,Shengmao Liu,Xiao Liu,Yao Lu,Xuedi Ma,Meifang Tang,Bo Wang,Guangbiao Wang,Honglong Wu,Renhua Wu,Xun Xu,Ye Yin,Dandan Zhang,Wenwei Zhang,Jiao Zhao,Meiru Zhao,Xiaole Zheng,Namrata Gupta,Neda Gharani,Toji Lh,Gerry Np,Resch Am,Jonathan Barker,Laurent Gil,Hunt Se,Gavin Kelman,Eugene Kulesha,Rasko Leinonen,McLaren Wm,Rajesh Radhakrishnan,Asier Roa,Dmitriy Smirnov,Smith Re,Ian Streeter,Anja Thormann,Iliana Toneva,Brendan Vaughan,Russell J. Grocock,Sean Humphray,Terena James,Zoya Kingsbury,R. Sudbrack,Albrecht Mw,Amstislavskiy Vs,Borodina Ta,Matthias Lienhard,Florian Mertes,Marc Sultan,Bernd Timmermann,Yaspo Ml,Lucinda Fulton,Robert S. Fulton,Victor Ananiev,Zinaida Belaia,Dimitriy Beloslyudtsev,Nathan Bouk,Chao Chen,Deanna M. Church,Robert M. Cohen,Charles Cook,John Garner,Timothy Hefferon,Mikhail Kimelman,Chunlei Liu,John Lopez,Peter Meric,Chris O’Sullivan,Yuri Ostapchuk,Lon Phan,Sergiy Ponomarov,Valerie A. Schneider,Eugene Shekhtman,Karl Sirotkin,Douglas J. Slotta,Hua Zhang,Senduran Balasubramaniam,John Burton,Petr Danecek,Keane Tm,A. Kolb Kokocinski,James Stalker,Michael A. Quail,Davies Cj,Jeremy Gollub,Teresa Webster,Brant Wong,Yiping Zhan,Campbell Cl,Anthony Marcketta,Lilian Antunes,Matthew N. Bainbridge,Aniko Sabo,Zhuoyi Huang,Coin Lj,Lin Fang,Qibin Li,Zhenyu Li,Haoxiang Lin,Binghang Liu,Ruibang Luo,Haojing Shao,Yinlong Xie,Chen Ye,Chang Yu,Fan Zhang,Hancheng Zheng,Zhu Hongmei,Garrison Ep,Deniz Kural,Lee Wp,Leong Wf,Michael Strömberg,Ward An,Jiantao Wu,Mengyao Zhang,Daly Mj,DePristo Ma,Eric Banks,Gaurav Bhatia,G. Del Angel,Giulio Genovese,Heng Li,Nemesh Jc,Poplin Re,Yoon Sc,Jayon Lihm,Vladimir Makarov,Srikanth Gottipati,Alon Keinan,Rodriguez Flores Jl,Fritz Mh,Kathryn Beal,Avik Datta,Javier Herrero,Ritchie Gr,Daniel R. Zerbino,Sabeti Pc,Ilya Shlyakhter,Schaffner Sf,Joseph J. Vitti,Cooper Dn,Ball Ev,Stenson Pd,Bret Barnes,Markus J. Bauer,Cheetham Rk,Anthony J. Cox,Michael A. Eberle,Scott Kahn,Lisa Murray,John F. Peden,Richard Shaw,Kenny Ee,MacArthur Dg,Monkol Lek,Ralf Herwig,Koboldt Dc,David E. Larson,Simon Gravel,Anand Swaroop,Emily Y. Chew,Tuuli Lappalainen,Yaniv Erlich,Melissa Gymrek,Willems Tf,Simpson Jt,Shriver Md,Rosenfeld Ja,Bustamante Cd,Montgomery Sb,De La Vega Fm,Byrnes Jk,Carroll Aw,DeGorter Mk,Phil Lacroute,Maples Bk,Martin Ar,A. Moreno Estrada,Shringarpure Ss,Fouad Zakharia,Eran Halperin,Yael Baran,Jaeho Hwang,Dariusz Plewczynski,Kamen Radew,Hyland Fc,Craig Dw,Alexis Christoforides,Nils Homer,Tyler Izatt,Kurdoglu Aa,Sinari Sa,Kevin Squire,Chunlin Xiao,Burchard Eg,Hernandez Rd,Gignoux Cr,David Haussler,Katzman Sj,Kent Wj,Bryan Howie,A. Ruiz Linares,Dermitzakis Et,Devine Se,Kang Hm,Thomas W. Blackwell,Sean Caron,Wei Chen,Lars G. Fritsche,Christian Fuchsberger,Bingshan Li,Robert H. Lyons,Chris Scheller,Carlo Sidore,Shiya Song,Elzbieta Sliwerska,Daniel Taliun,Adrian Tan,Ryan P. Welch,Wing Mk,Xiaowei Zhan,Philip Awadalla,Alan Hodgkinson,Gerton Lunter,Marchini Jl,Simon Myers,Claire Churchhouse,Olivier Delaneau,A. Gupta Hinch,Warren W. Kretzschmar,Zamin Iqbal,Iain Mathieson,Andrew J. Rimmer,Xifara Dk,Oleksyk Tk,Yunxin Fu,Momiao Xiong,Lynn B. Jorde,David J. Witherspoon,Jinchuan Xing,Browning Bl,Ekta Khurana,C. Tyler Smith,Albers Ca,Qasim Ayub,Yuan Chen,Vincenza Colonna,Luke Jostins,Yali Xue,Gerstein Mb,Suganthi Balasubramanian,Declan Clarke,Harmanci Ao,Mike Jin,Dong-Hoon Lee,Jeremy Liu,Mu Xj,Christopher Hartl,Khalid Shakir,Jeremiah D. Degenhardt,Casale Fp,Oliver Stegle,Ira M. Hall,Vineet Bafna,Jacob J. Michaelson,Mills Re,Tenghui Chen,Ben Blackburne,Lindsay Sj,Zemin Ning,Hugo Y. K. Lam,Cristina Sisu,Danny Challis,Evani Us,James T. Lu,Uma Nagaswamy,Jin Yu,Wangshen Li,H. Min Kang,Lukas Habegger,Haiyuan Yu,Fiona Cunningham,Ian Dunham,Kasper Lage,Jespersen Jb,Heiko Horn,Donghoon Kim,Rob DeSalle,Apurva Narechania,Sayres Ma,Mendez Fl,Poznik Gd,Underhill Pa,Lachlan J. M. Coin,David Mittelman,Ruby Banerjee,Maria Cerezo,Fitzgerald Tw,Sandra Louzada,Andrea Massaia,Fengtang Yang,Divya Kalra,Walker Hale,Xu Dan,Barnes Kc,Christine Beiswanger,Hongyu Cai,Hongzhi Cao,Brenna M. Henn,Danielle Jones,Kaye Js,Alastair Kent,Angeliki Kerasidou,R. Mathias,Ossorio Pn,Michael Parker,Rotimi Cn,Royal Cd,Karla Sandoval,Yeyang Su,Zhongming Tian,Sarah A. Tishkoff,Marc Via,Yuhong Wang,Huanming Yang,Ling Yang,Jiayong Zhu,Walter F. Bodmer,Gabriel Bedoya,Zhiming Cai,Yang Gao,Jiayou Chu,Leena Peltonen,A. Garcia Montero,Alberto Orfao,Julie Dutil,Martinez Cruzado Jc,Mathias Ra,Anselm Hennis,Harold Watson,Colin A. McKenzie,Firdausi Qadri,Regina C. LaRocque,Xiaoyan Deng,Danny Asogun,Onikepe A. Folarin,Christian T. Happi,Omonwunmi Omoniwa,Matt Stremlau,Ridhi Tariyal,M Jallow,Joof Fs,Tumani Corrah,Kirk A. Rockett,Dominic P. Kwiatkowski,Jaspal S. Kooner,Hiên Tt,Dunstan Sj,Hang Nt,Richard Fonnie,Robert F. Garry,Lansana Kanneh,Lina M. Moses,John S. Schieffelin,Grant Ds,Carla Gallo,Giovanni Poletti,Danish Saleheen,Asif Rasheed,Brooks Ld,Felsenfeld Al,McEwen Je,Yekaterina Vaydylevich,Audrey Duncanson,Michael Dunn,Schloss Ja,Abecasis G. R. Mills Re,A. Bashir +494 more
TL;DR: An integrated set of eight structural variant classes comprising both balanced and unbalanced variants, which are constructed using short-read DNA sequencing data and statistically phased onto haplotype blocks in 26 human populations are described.