K
Kristina I. Rother
Researcher at National Institutes of Health
Publications - 120
Citations - 8797
Kristina I. Rother is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Type 1 diabetes & Diabetes mellitus. The author has an hindex of 44, co-authored 120 publications receiving 7538 citations.
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Journal ArticleDOI
A Single Course of Anti-CD3 Monoclonal Antibody hOKT3γ1(Ala-Ala) Results in Improvement in C-Peptide Responses and Clinical Parameters for at Least 2 Years after Onset of Type 1 Diabetes
Kevan C. Herold,Stephen E. Gitelman,Umesh Masharani,William Hagopian,Brygida Bisikirska,David Donaldson,Kristina I. Rother,Beverly Diamond,David M. Harlan,Jeffrey A. Bluestone +9 more
TL;DR: It is concluded that treatment with the anti-CD3 monoclonal antibody hOKT3γ1(Ala-Ala) results in improved C-peptide responses and clinical parameters in type 1 diabetes for at least 2 years in the absence of continued immunosuppressive medications.
Journal ArticleDOI
Diabetes treatment--bridging the divide.
TL;DR: The disease mechanisms and treatments for the different types of diabetes, regardless of the inciting event, are discussed by Dr Kristina Rother.
Journal ArticleDOI
SGLT2 Inhibitors May Predispose to Ketoacidosis
TL;DR: There are several biologically plausible mechanisms whereby this class of drugs has the potential to increase the risk of developing diabetic ketoacidosis.
Journal ArticleDOI
JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies
Gina A. Montealegre Sanchez,Adam L Reinhardt,Suzanne E. Ramsey,Helmut Wittkowski,Philip J. Hashkes,Yackov Berkun,Susanne Schalm,Sara Murias,Jason Dare,Diane Brown,Deborah L. Stone,Ling Gao,Thomas Klausmeier,Dirk Foell,Adriana Almeida de Jesus,Dawn Chapelle,Hanna Kim,Samantha Dill,Robert A. Colbert,Laura Failla,B. Kost,Michelle O'Brien,James C. Reynolds,Les R. Folio,Katherine R. Calvo,Scott M. Paul,Nargues Weir,Alessandra Brofferio,Ariane Soldatos,Angelique Biancotto,Edward W. Cowen,John J. Digiovanna,Massimo Gadina,Andrew Lipton,Colleen Hadigan,Steven M. Holland,Joseph A. Fontana,Ahmad Samer Alawad,Rebecca J. Brown,Kristina I. Rother,Theo Heller,Kristina M Brooks,Parag Kumar,Stephen R. Brooks,Meryl Waldman,Harsharan K. Singh,Volker Nickeleit,Maria Silk,Apurva Prakash,Jonathan Janes,Seza Ozen,Paul G. Wakim,Paul A. Brogan,William L. Macias,Raphaela Goldbach-Mansky +54 more
TL;DR: Upon baricitinib treatment, clinical manifestations and inflammatory and IFN biomarkers improved in patients with the monogenic interferonopathies CANDLE, SAVI, and other interfer onopathies.
Journal ArticleDOI
Survival After Pancreas Transplantation in Patients With Diabetes and Preserved Kidney Function
Jeffrey M. Venstrom,Maureen A. McBride,Kristina I. Rother,Boaz Hirshberg,Trevor J. Orchard,David M. Harlan +5 more
TL;DR: From 1995-2000, survival for those with diabetes and preserved kidney function and receiving a solitary pancreas transplant was significantly worse compared with the survival of waiting-list patients receiving conventional therapy.