K
Kristoffer T.G. Rigbolt
Researcher at University of Southern Denmark
Publications - 47
Citations - 2754
Kristoffer T.G. Rigbolt is an academic researcher from University of Southern Denmark. The author has contributed to research in topics: Phosphorylation & Stable isotope labeling by amino acids in cell culture. The author has an hindex of 22, co-authored 46 publications receiving 2328 citations. Previous affiliations of Kristoffer T.G. Rigbolt include University of Freiburg.
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Journal ArticleDOI
System-Wide Temporal Characterization of the Proteome and Phosphoproteome of Human Embryonic Stem Cell Differentiation
Kristoffer T.G. Rigbolt,Tatyana A. Prokhorova,Vyacheslav Akimov,Jeanette Henningsen,Jeanette Henningsen,Pia Thermann Johansen,Irina Kratchmarova,Moustapha Kassem,Moustapha Kassem,Matthias Mann,Jesper V. Olsen,Blagoy Blagoev +11 more
TL;DR: Cellular events underlying the pluripotency of human embryonic stem cells (hESCs) are elucidated and a core hESC phosphoproteome of sites with similar robust changes in response to the two distinct treatments is identified.
Journal ArticleDOI
MSQuant, an Open Source Platform for Mass Spectrometry-Based Quantitative Proteomics
Peter Mortensen,Joost W. Gouw,Jesper V. Olsen,Shao En Ong,Kristoffer T.G. Rigbolt,Jakob Bunkenborg,Jürgen Cox,Leonard J. Foster,Albert J. R. Heck,Blagoy Blagoev,Jens S. Andersen,Matthias Mann +11 more
TL;DR: An open source software environment, called MSQuant, which allows visualization and validation of peptide identification results directly on the raw mass spectrometric data, and iteratively recalibrates MS data thereby significantly increasing mass accuracy leading to fewer false positive peptide identifications.
Journal ArticleDOI
Dynamics of the skeletal muscle secretome during myoblast differentiation
Jeanette Henningsen,Kristoffer T.G. Rigbolt,Blagoy Blagoev,Bente Klarlund Pedersen,Irina Kratchmarova +4 more
TL;DR: Analysis of the intracellular levels of members of the semaphorin family and their corresponding secretion dynamics demonstrated that the release ofsecreted proteins is tightly regulated by the secretory pathway, the stability of the protein, and/or the processing of secreted proteins.
Journal ArticleDOI
GProX, a User-Friendly Platform for Bioinformatics Analysis and Visualization of Quantitative Proteomics Data
TL;DR: The Graphical Proteomics Data Explorer (GProX) represents a powerful approach to proteomics data analysis providing proteomics experimenters with a toolbox for bioinformatics analysis of quantitative proteomic data.
Journal ArticleDOI
Hepatic transcriptome signatures in patients with varying degrees of nonalcoholic fatty liver disease compared with healthy normal-weight individuals
Malte P. Suppli,Kristoffer T.G. Rigbolt,Sanne Skovgård Veidal,Sara Heebøll,Peter Lykke Eriksen,Mia Demant,Jonatan I. Bagger,Jens Nielsen,Denise Oró,Sebastian W. Thrane,Asger Lund,Charlotte Strandberg,Merete J Kønig,Tina Vilsbøll,Niels Vrang,Karen Louise Thomsen,Henning Grønbæk,Jacob Jelsing,Henrik H. Hansen,Filip K. Knop +19 more
TL;DR: Application of immunohistochemical markers of hepatocyte injury may serve as a more objective tool for distinguishing NASH from NAFL, facilitating improved resolution of hepatic molecular changes associated with progression of NAFLD.