L
L. Trevor Young
Researcher at University of Toronto
Publications - 144
Citations - 16200
L. Trevor Young is an academic researcher from University of Toronto. The author has contributed to research in topics: Bipolar disorder & Lithium (medication). The author has an hindex of 62, co-authored 143 publications receiving 15122 citations. Previous affiliations of L. Trevor Young include University of British Columbia & Mental Health Research Institute.
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Journal ArticleDOI
Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: update 2013.
Lakshmi N. Yatham,Sidney H. Kennedy,Sagar V. Parikh,Ayal Schaffer,Serge Beaulieu,Martin Alda,Claire O'Donovan,Glenda MacQueen,Roger S. McIntyre,Verinder Sharma,Arun V. Ravindran,L. Trevor Young,Roumen Milev,David J. Bond,Benicio N. Frey,Benjamin I. Goldstein,Beny Lafer,Boris Birmaher,Kyooseob Ha,Willem A. Nolen,Michael Berk,Michael Berk +21 more
TL;DR: The Canadian Network for Mood and Anxiety Treatments published guidelines for the management of bipolar disorder in 2005, with updates in 2007 and 2009, and this third update, in conjunction with the International Society for Bipolar Disorders, reviews new evidence and is designed to be used in conjunctionWith the previous publications.
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Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication.
TL;DR: Findings are consistent with recent studies measuring CREB levels in this same subject sample, and support current animal and cellular models of antidepressant function.
Journal ArticleDOI
Course of illness, hippocampal function, and hippocampal volume in major depression
Glenda MacQueen,Stephanie Campbell,Bruce S. McEwen,Kathryn Macdonald,Shigeko Amano,Russell T. Joffe,Claude Nahmias,L. Trevor Young +7 more
TL;DR: Comparing hippocampal function, as assessed by performance on hippocampal-dependent recollection memory tests, and hippocampal volumes, as measured in a 1.5-T magnetic resonance imager, in depressed subjects experiencing a postpubertal onset of depression revealed a significant logarithmic association between illness duration and hippocampusal volume.
Journal ArticleDOI
Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: update 2009.
Lakshmi N. Yatham,Sidney H. Kennedy,Ayal Schaffer,Sagar V. Parikh,Serge Beaulieu,Claire O'Donovan,Glenda MacQueen,Roger S. McIntyre,Verinder Sharma,Arun V. Ravindran,L. Trevor Young,Allan H. Young,Martin Alda,Roumen Milev,Eduard Vieta,Joseph R. Calabrese,Michael Berk,Kyooseob Ha,Flávio Kapczinski +18 more
TL;DR: New data support the use of quetiapine monotherapy and adjunctive therapy for the Prevention of manic and depressive events, aripiprazole monotherapy for the prevention of manic events, and risperidone long-acting injection monotherapy
Journal ArticleDOI
Decreased levels of glutathione, the major brain antioxidant, in post-mortem prefrontal cortex from patients with psychiatric disorders.
TL;DR: The finding that GSH levels are reduced in post-mortem prefrontal cortex suggests that these patient groups may be more susceptible to oxidative stress.