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L. Trevor Young

Researcher at University of Toronto

Publications -  144
Citations -  16200

L. Trevor Young is an academic researcher from University of Toronto. The author has contributed to research in topics: Bipolar disorder & Lithium (medication). The author has an hindex of 62, co-authored 143 publications receiving 15122 citations. Previous affiliations of L. Trevor Young include University of British Columbia & Mental Health Research Institute.

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Gene expression differences in bipolar disorder revealed by cDNA array analysis of post-mortem frontal cortex.

TL;DR: The results suggest that the down‐regulation of TGF‐β1 may lead to various neurotoxic insults potentially involved in the etiology of certain mood disorders.
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Hippocampal volumes in bipolar disorders: opposing effects of illness burden and lithium treatment.

TL;DR: Hajek T, Cullis J, Novak T, Kopecek M, Höschl C, Blagdon R, O’Donovan C, Bauer M, Young L T, MacQueen G, Alda M. Hippocampal volumes in bipolar disorders: opposing effects of illness burden and lithium treatment.
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A randomized double-blind sham-controlled comparison of unilateral and bilateral repetitive transcranial magnetic stimulation for treatment-resistant major depression

TL;DR: The remission rates differed significantly among the three treatment groups using a modified intention to treat analysis that excluded subjects who did not respond to electroconvulsive therapy (ECT) during the current episode.
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Nod-like receptor pyrin containing 3 (NLRP3) in the post-mortem frontal cortex from patients with bipolar disorder: A potential mediator between mitochondria and immune-activation

TL;DR: The findings suggest that immune-activation in the frontal cortex may occur both in patients with BD and schizophrenia, while complex I dysfunction and NLRP3-inflammasome activation may be more specific to BD.