L
Lana Popova
Researcher at Cell Signaling Technology
Publications - 11
Citations - 2424
Lana Popova is an academic researcher from Cell Signaling Technology. The author has contributed to research in topics: Antigen & Myeloid leukemia. The author has an hindex of 9, co-authored 11 publications receiving 2241 citations. Previous affiliations of Lana Popova include Harvard University.
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Journal ArticleDOI
Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus.
Evelyn A. Kurt-Jones,Lana Popova,Laura Kwinn,Lia M. Haynes,Les P. Jones,Ralph A. Tripp,Edward E. Walsh,Mason W. Freeman,Douglas T. Golenbock,Larry J. Anderson,Robert W. Finberg,Robert W. Finberg +11 more
TL;DR: A common receptor activation pathway can initiate innate immune responses to both bacterial and viral pathogens.
Journal ArticleDOI
Long-Lived Plasma Cells Are Contained within the CD19(-)CD38(hi)CD138(+) Subset in Human Bone Marrow.
Jessica L. Halliley,Jessica L. Halliley,Christopher M. Tipton,Jane L. Liesveld,Alexander F. Rosenberg,Jaime Darce,Ivan V. Gregoretti,Lana Popova,Denise A. Kaminiski,Christopher F. Fucile,Igor Albizua,Shuya Kyu,Kuang-Yueh Chiang,Kyle T. Bradley,Richard Burack,Mark K. Slifka,Erika Hammarlund,Hao Wu,Liping Zhao,Edward E. Walsh,Ann R. Falsey,Troy D. Randall,Wan Cheung Cheung,Iñaki Sanz,F. Eun-Hyung Lee +24 more
TL;DR: Human LLPCs are defined and a mechanism for the life-long maintenance of anti-viral antibodies in the serum is provided and probably represents the B cell response's "historical record" of antigenic exposure.
Journal ArticleDOI
A proteomics approach for the identification and cloning of monoclonal antibodies from serum
Wan Cheung Cheung,Sean A. Beausoleil,Xiaowu Zhang,Shuji Sato,Sandra M Schieferl,James Wieler,Beaudet Jason G,Ramenani Ravi K,Lana Popova,Michael J. Comb,John Rush,Roberto D. Polakiewicz +11 more
TL;DR: A proteomics approach that identifies antigen-specific antibody sequences directly from circulating polyclonal antibodies in the serum of an immunized animal and isolated monoclonal antibodies for five antigens from the sera of immunized rabbits and mice is described.
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Proteomics-directed cloning of circulating antiviral human monoclonal antibodies
Shuji Sato,Sean A. Beausoleil,Lana Popova,Beaudet Jason G,Ramenani Ravi K,Xiaowu Zhang,James Wieler,Sandra M Schieferl,Wan Cheung Cheung,Roberto D. Polakiewicz +9 more
TL;DR: Trackster’s use of data subsets to reduce analysis computation time is applicable to a wide set of genomic tools, but tools that use data from many or all genomic regions to build a global model require additional support to work with Trackster.
Journal ArticleDOI
A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemia.
Ting-Lei Gu,Thomas Mercher,Jeffrey W. Tyner,Valerie Goss,Denise K. Walters,Melanie G. Cornejo,Cynthia Reeves,Lana Popova,Kimberly Lee,Michael Heinrich,John Rush,Masanori Daibata,Isao Miyoshi,D. Gary Gilliland,Brian J. Druker,Roberto D. Polakiewicz +15 more
TL;DR: A discovery platform consisting of immunoaffinity profiling coupled to mass spectrometry that identifies large numbers of tyrosine-phosphorylated proteins, including active kinases in acute myeloid leukemia revealed the presence of an activated colony-stimulating factor 1 receptor (CSF1R) kinase in the acute megakaryoblastic leukemia cell line MKPL-1.