L
Lance Parsons
Researcher at Princeton University
Publications - 38
Citations - 3721
Lance Parsons is an academic researcher from Princeton University. The author has contributed to research in topics: Genome & Herpes simplex virus. The author has an hindex of 22, co-authored 37 publications receiving 3045 citations. Previous affiliations of Lance Parsons include Arizona State University.
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Journal ArticleDOI
Subspace clustering for high dimensional data: a review
TL;DR: A survey of the various subspace clustering algorithms along with a hierarchy organizing the algorithms by their defining characteristics is presented, comparing the two main approaches using empirical scalability and accuracy tests and discussing some potential applications where sub space clustering could be particularly useful.
Journal ArticleDOI
Four Key Steps Control Glycolytic Flux in Mammalian Cells.
Lukas B. Tanner,Alexander G. Goglia,Monica H. Wei,Talen Sehgal,Lance Parsons,Junyoung O. Park,Eileen White,Jared E. Toettcher,Joshua D. Rabinowitz +8 more
TL;DR: Flux control in glycolysis is concentrated in four key enzymatic steps, specifically upregulated by the Ras oncogene: optogenetic Ras activation rapidly induces the transcription of isozymes catalyzing these four steps and enhances gly colysis.
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Evolving feature selection
Huan Liu,Edward R. Dougherty,Jennifer G. Dy,Kari Torkkola,Eugene Tuv,Hanchuan Peng,Chris Ding,Fuhui Long,Michael E. Berens,Lance Parsons,Zheng Zhao,Lei Yu,George Forman +12 more
TL;DR: This article considers feature-selection overfitting with small-sample classifier design; feature selection for unlabeled data; variable selection using ensemble methods; minimum redundancy-maximum relevance feature selection; and biological relevance infeature selection for microarray data.
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The Oxytricha trifallax Macronuclear Genome: A Complex Eukaryotic Genome with 16,000 Tiny Chromosomes
Estienne C. Swart,John R. Bracht,Vincent Magrini,Patrick Minx,Xiao Chen,Yi Zhou,Jaspreet S. Khurana,Aaron David Goldman,Mariusz Nowacki,Mariusz Nowacki,Klaas Schotanus,Seolkyoung Jung,Robert S. Fulton,Amy Ly,Sean McGrath,Kevin Haub,Jessica L. Wiggins,Donna Storton,John C. Matese,Lance Parsons,Wei-Jen Chang,Michael S. Bowen,Nicholas A. Stover,Thomas A. Jones,Sean R. Eddy,Glenn Herrick,Thomas G. Doak,Richard K. Wilson,Elaine R. Mardis,Laura F. Landweber +29 more
TL;DR: With more chromosomes than any other sequenced genome, the macronuclear genome of Oxytricha trifallax has a unique and complex architecture, including alternative fragmentation and predominantly single-gene chromosomes.
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Extrachromosomal circular DNA is common in yeast
TL;DR: It is proposed that eccDNAs may be precursors to the copy number variation in eukaryotic genomes characteristic of both the evolutionary process and cancer progression, and that they might contribute substantially to genetic variation and evolution.